Department of Pharmacology & Chemical Biology at the University of Pittsburgh
Jill M. Siegfried, PhD
Adjunct Professor
Head of the Department of Pharmacology 6-120 Jackson Hall, 321 Church St. SE
Minneapolis, MN 55455-0217

Phone: 612-625-9997

Fax: 612-625-8408


BA (Molecular Biology and German), Wellesley College, Wellesley, MA, 1976. MPhil (Pharmacology), Yale University, New Haven, CT, 1978. PhD (Pharmacology), Yale University, New Haven, CT, 1981. Postdoctoral Fellow, Cancer Research Center, University of North Carolina, Chapel Hill, NC, 1980-1982.

Research Areas
Protein Kinases & Phosphatases
Cancer Pharmacology
Photo of Jill M. Siegfried, PhD

Important Publications
Dulak AM, CT Gubish, LP Stabile, C Henry and JM SiegfriedHGF-independent potentiation of EGFR action by c-Met. Oncogene 2011 Mar 21. [Epub ahead of print]
Stabile LP, S Dacic, SR Land, DE Lenzner, R Dhir, M Acquafondata, RJ Landreneau, JR Grandis and JM Siegfried. Combined analysis of estrogen receptor {beta}-1 and progesterone receptor expression identifies lung cancer patients with poor outcome. Clin Cancer Res 17:154-164, 2011.
Stabile LP, ME Rothstein, P Keohavong, D Lenzner, SR Land, AL Gaither-Davis, KJ Kim, N Kaminski and JM SiegfriedTargeting of both the c-Met and EGFR pathways results in additive Inhibition of lung tumorigenesis in transgenic mice.  Cancers (Basel) 2:2153-2170, 2010.
Ostroff RM, WL Bigbee, W Franklin, L Gold, M Mehan, YE Miller, HI Pass, WN Rom, JM Siegfried, A Stewart, JJ Walker, JL Weissfeld, S Williams, D Zichi and EN Brody.  Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer. PLoS One 5:e15003, 2010.
Egloff AM, ME Rothstein, R Seethala, JM Siegfried, JR Grandis and LP Stabile.  Cross-talk between estrogen receptor and epidermal growth factor in head and neck squamous cell carcinoma.  Clin Cancer Res 15:6529-6540, 2009.
Siegfried JM, PA Hershberger and LP Stabile.  Estrogen receptor signaling in lung cancer.  Seminars in Oncology 36:524-531, 2009.

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