Courtney Andersen studies the role of estrogen receptor-alpha in ovarian cancer.
Chris Barnes investigates the structural details by which transcription factor activity regulates RNA Polymerase II during the universal process of eukaryotic gene expression.
Soma Jobaggy studies nitrated fatty acid pharmacology and the antioxidant response in hypertensive end-organ damage.
Allison Nagle studies growth factor receptor signaling in breast cancer.
Elias Aizenman, PhD
Professor, Neurobiology
E1456 Biomedical Science Tower
Pittsburgh, PA 15261

Email:
redox@pitt.edu
Phone: 412-648-9434

Fax: 412-648-1441


Education
BA (Biology), Boston University, 1981.
PhD (Toxicology), Johns Hopkins University, 1985


Research Areas
Neuropharmacology
Photo of Elias Aizenman, PhD

Research in Dr. Aizenman's laboratory is directed towards investigating apoptotic and non-apoptotic neuronal cell death processes following the liberation of intracellular zinc.





Important Publications
Redman, P.Y., K. He, K.A. Hartnett, B.S. jefferson, L. Hu, PlA. Rosenberg, E.S. Levitan and E. Aizenman. Apoptotic surge of potassium currents is mediated by p38 phosphor7lation of Kv2.1. Proc. Natl. Acad. Sci. (U.S.A.) 2007; 104-3568-3573.
Redman, P.Y., B.S. Jefferson, C.B. Ziegler, O.V. Mortensen, G.E. Torres, E.S. Levitan and E. Aizenman. A vital role of Kv channels in dopamine transporter-mediated 6-hydroxydopamine neurotoxicity. Neuroscience  2006; 143:1-6.
He, K., J. Huang, C.F. Lagenaur and  E. Aizenman. Methylisothiazolinone, a neurotoxic biocide, disrupts the association of SRC family tyrosine kinases with focal adhesion kinase in developing cortical neurons. J. Pharmacol. Exp. Therap. 2006; 317:1320-1329.
Pal, S., K. Takimoto, E. Aizenman and E.S. Levitan. Apoptotic surface delivery of K(+) channels. Cell Death & Differentiation 2006; 13:661-667.

STUDENT NEWS



Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Outcomes: 

Time to dissertation Defense
, last five graduating classes:  4.6 years, Completion Rate: 86.49%

First Author Publications (All students, past 5 year mean):  2.03;   Total Publications: 5.10

F-series Grants (F30/F31) (All Students, past 5 year mean):  12/34 (35%) 


Ranked #9 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty-four consecutive years




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