Courtney Andersen studies the role of estrogen receptor-alpha in ovarian cancer.
Chris Barnes investigates the structural details by which transcription factor activity regulates RNA Polymerase II during the universal process of eukaryotic gene expression.
Soma Jobaggy studies nitrated fatty acid pharmacology and the antioxidant response in hypertensive end-organ damage.
Allison Nagle studies growth factor receptor signaling in breast cancer.
Pei Tang, PhD
Professor, Anesthesiology and Perioperative Medicine and Structural Biology
2049 Biomedical Science Tower 3
3501 5th Ave, Pittsburgh, PA 15213

Phone: 412-383-9798

Fax: 412-648-9009


BS (Chemistry), University of Science and Technology of China, 1982.
PhD (Chemistry), State University of New York at Stony Brook, 1990.
Postdoctoral Fellow, University of California, Berkeley Lawrence Berkeley National Lab, 1990-93

Research Areas
Photo of Pei Tang, PhD

Important Publications
Bondarenko V, Y Xu and P Tang. Structure of the first transmembrane domain of the neuronal acetylcholine receptor b2 subunit.  Biophysical J 92:1616-1622, 2007.
Szarecka A, X Yan and P Tang.  Dynamics of heteropentameric nicotinic acetylcholine receptor:  Implications of the gating mechanism.  Proteins:  Structure, Function and Bioinformatics 68(4):948-960, 2007.
Liu Z, Y Xu Y and P Tang.  Steered molecular dynamics simulations of Na+ permeation across the gramicidin A channel.  J Phys Chem B 110:2789-12795, 2006.
Yonkunas MJ, Y Xu and P Tang. Anesthetic interaction with ketosteroid isomerase: Insights from molecular dynamics simulations. Biophysical J 89:2350-2356, 2005.
Saladino AC, Y Xu and P Tang. Homology modeling and molecular dynamics simulations of transmembrane domain structure of human neuronal nicotinic acetylcholine receptor. Biophysical J 88:1009-1017, 2005.
Liu Z, Y Xu Y and P Tang.  MD simulations of C2F6 effects on gramicidin A: Implication of mechanisms of general anesthesia. Biophysical J 88:3784-3791, 2005.


Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings


Time to dissertation Defense
, last five graduating classes:  4.6 years, Completion Rate: 86.49%

First Author Publications (All students, past 5 year mean):  2.03;   Total Publications: 5.10

F-series Grants (F30/F31) (All Students, past 5 year mean):  12/34 (35%) 

Ranked #9 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty-four consecutive years

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