Courtney Andersen studies the role of estrogen receptor-alpha in ovarian cancer.
Chris Barnes investigates the structural details by which transcription factor activity regulates RNA Polymerase II during the universal process of eukaryotic gene expression.
Soma Jobaggy studies nitrated fatty acid pharmacology and the antioxidant response in hypertensive end-organ damage.
Allison Nagle studies growth factor receptor signaling in breast cancer.
Anthony Kanai, PhD
Associate Professor, Medicine
A1224 Scaife Hall
Pittsburgh, PA 15261

Phone: 412-624-1430

Fax: 412-648-7197


BS (Biochemistry), Duquesne University, 1980.
MS (Pharmacology), Duquesne University, 1983.
PhD (Physiology), University of Pittsburgh, 1992.

Research Areas
Pharmacology of Cell and Organ Systems
Photo of Anthony Kanai, PhD

Important Publications

Kanai A. Afferent mechanisms.  Handbook of Experimental Pharmacology 202:171-205, 2011

Kanai A, I Zabbarova, Y Ikeda, N Yoshimura, L Birder, A Hanna-Mitchell and W de Groat.  Sophisticated models and methods for studying neurogenic bladder dysfunction.  Neurology & Urodynamics 30:658-667, 2011.
Drake M, C Tannenbaum and A Kanai.  Potential insights into lower urinary tract function derived from CNS imaging.  Neurology and Urodynamics 26:13-19, 2010.

McCarthy C, I Zabbarova, P Brumovsky, J Roppolo, G Gebhart and A Kanai.  Spontaneous contractions evoke afferent nerve firing in detrusor overactivity. Journal of Urology 181:1459-1466, 2009.

Ikeda Y, L Birder, C Buffington, J Roppolo and A Kanai.  Mucosal muscarinic receptors enhance bladder activity in cats with feline interstitial cystitis.  Journal of Urology 181:1415-1422, 2009.

Ikeda Y and A Kanai.  Urotheliogenic modulation of intrinsic detrusor activity in spinal cord transected rat bladders:  The role of mucosal muscarinic receptors.  American Journal of Physiology 295:F454-F461, 2008.

Zabbarova I and A Kanai.  Mitochondrial targeting of radioprotectants Molecular Intervention 8:294-302, 2008.

Kanai A, J Roppolo, C Tai, L Birder, D Griffiths, Y Ikeda, I Zabbarova, W de Groat and C Fry. Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic antagonists. American Journal of Physiology 292:F1065-F1072, 2007.


1/10/2019 12:00 PM Pharmacology & Chemical Biology Seminar Series
Mitchell Lazar, M.D., Ph.D.

1/17/2019 12:00 PM Pharmacology & Chemical Biology Seminar Series
Mark Jay Shlomchik, MD, PhD

1/19/2019 12:00 PM Pharmacology & Chemical Biology Seminar Series
Mitchell Lazar, MD, PhD

Pharmacology and Chemical Biology Event Calendar

Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Outcomes:  Time to disseration, last five graduating clasess:  4.5 years, Completion Rate: 84.8%

Ranked #12 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty two consecutive years

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