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University of Pittsburgh

Joseph Galley

Predoctoral Fellow
1253 E Biomedical Science Tower
jcg59@pitt.edu

Education

B.A. Biochemistry, Washington & Jefferson College
 
Graduation
August 2021
Degree
PhD
Where Are They Now?
Post-doc at Children’s Hospital of Pittsburgh with Thiago Bruder

Research Summary

Discovery of novel mechanisms of vascular tone regulation through FoxO transcription factors
 
Headshot of Joseph Galley

Labs

Discovery of novel mechanisms of vascular tone regulation through FoxO transcription factors
 

Journal Articles

Galley JC, Hahn SA, Miller MP, Durgin BG, Jackson EK, Stocker SD, Straub AC. Angiotensin II augments renal vascular smooth muscle soluble GC expression via an AT1 receptor-forkhead box subclass O transcription factor signalling axis.  Br J Pharmacol. 2021 May 7. doi: 10.1111/bph.15522. Online ahead of print. PMID: 33963547

 
Galley JC, Durgin BG, Miller MP, Hahn SA, Yuan S, Wood KC, Straub AC. Antagonism of Forkhead Box Subclass O Transcription Factors Elicits Loss of Soluble Guanylyl Cyclase Expression.  Mol Pharmacol. 2019 Jun;95(6):629-637. doi: 10.1124/mol.118.115386. Epub 2019 Apr 15. PMID: 30988014   PMCID: PMC6527398
 
Alvarez RA, Miller MP, Hahn SA, Galley JC, Bauer E, Bachman T, Hu J, Sembrat J, Goncharov D, Mora AL, Rojas M, Goncharova E, Straub AC.   Targeting Pulmonary Endothelial Hemoglobin α Improves Nitric Oxide Signaling and Reverses Pulmonary Artery Endothelial Dysfunction.  Am J Respir Cell Mol Biol. 2017 Dec;57(6):733-744. doi: 10.1165/rcmb.2016-0418OC. PMID: 28800253  PMCID: PMC5765416

 
Galley JC, Straub AC.   Redox Control of Vascular Function.  Arterioscler Thromb Vasc Biol. 2017 Dec;37(12):e178-e184. doi: 10.1161/ATVBAHA.117.309945. PMID: 29162599  PMCID: PMC5751756
 

Awards and Honors

NIH T32 Fellowship Award; University of Pittsburgh, Department of Geriatric Medicine (September 2017-August 2018)
 
Louis J. Ignarro Cardiovascular Pharmacology Departmental Fellowship (September 2018-August 2019)
 
ASPET Highlighted Trainee Author Award, Molecular Pharmacology (June 2019)
 
NIH F31 Ruth L. Kirschstein Predoctoral Individual National Research Service Award; National Heart, Lung and Blood Institute (April 2020 – March 2023)
 

Sponsored Research

Department Fellowship