Department of Pharmacology & Chemical Biology at the University of Pittsburgh
Patricia Lynn Opresko, PhD
Professor, Environmental and Occupational Health
Hillman Cancer Center, 5117 Centre Avenue, Suite 2.6a
Pittsburgh, PA 15213

Phone: 412-623-7764

Fax: 412-623-7807

2000 - Pennsylvania State University College of Medicine, Hershey, PA - PhD in Biochemistry and Molecular Biology

1994  - DeSales University, Center Valley, PA - Bachelors of Science in Chemistry and Biology
Photo of Patricia Lynn Opresko, PhD

My lab studies DNA damage and repair at telomeres.  Telomeres are the caps at chromosome ends that are essential for preserving the genome.  When chromosomes lose their telomere caps the cells age and this contributes to the onset of degenerative diseases with aging.  If chromosomes lose their telomere caps in pre-cancerous cells then this causes genetic alterations that hasten the progression to cancer.  Understanding how telomere damage and repair happens should lead to new intervention strategies aimed at preserving these regions of the genome that are so critical for protecting our chromosomes and maintaining youthful cells.   

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