Courtney Andersen studies the role of estrogen receptor-alpha in ovarian cancer.
Chris Barnes investigates the structural details by which transcription factor activity regulates RNA Polymerase II during the universal process of eukaryotic gene expression.
Soma Jobaggy studies nitrated fatty acid pharmacology and the antioxidant response in hypertensive end-organ damage.
Allison Nagle studies growth factor receptor signaling in breast cancer.
Richard Steinman, MD
Associate Professor, Medicine
2.18 Hillman Cancer Center
Pittsburgh, PA 15213

Email:
steinman@pitt.edu
Phone: 412-623-3237

Fax: 412-623-7778


Education

B.S. (Chemistry), Haverford College, 1978. M.D. (Medicine), University of Pennsylvania, 1987. Ph.D. (Biochemistry), University of Pennsylvania, 1988.



Research Areas
Cancer Pharmacology
Photo of Richard Steinman, MD





Important Publications
Steinman RA, Wang Q, Gasparetto M, Robinson LJ, Liu X, Lenzner DE, Hou J, Smith C, Wang Q. Deletion of the RNA-editing enzyme ADAR1 causes regression of established chronic myelogenous leukemia in mice. Int J Cancer. 2013 Apr 15;132(8):1741-50.
Steinman RA, Robinson AR, Feghali-Bostwick CA. Antifibrotic effects of roscovitine in normal and scleroderma fibroblasts. PLoS One 2012;7(11):e48560.
Sharma R, Wang Y, Zhoi P, Steinman RA and Wang Q. An essential role of RNA editing enzyme ADAR1 in mouse skin. J Dermatol Sci. 2011 Oct.64(1):70-2(2011)
Steinman RA, Wang Q. ADAR1 isoform involvement in embryonic lethality. Proc Natl Acad Sci USA. 2011 Jun 14:108(24):E199. Epub 2011 May 18.
S.H. Leuba and R.A. Steinman 2011 How to think like a single molecule: obtaining quantitative measurements on single DNA molecules and chromatin fibers in Biophysics of Protein-DNA Interactions. M.C. Williams and L.J. Maher, III, Eds. Springer, NY pp. 307-323.
Steinman RA. Cancer therapeutics: time to swim downstream? Oncologist 2011;16(10):1479-80.
Andraos-Selim C, Modzelewski RA and Steinman RA. Inter-institutional development of a poster-based cancer biology learning tool. J. Cancer Educ. 2010 Sep.25(3):413-7(2010). 
Steinman RA. mRNA stability control: A clandestine force in normal and malignant hematopoiesis. Leukemia 21(6):1158-1171, 2007.
Duensing A, L Ghanem, RA Steinman, Y Liu and S Duensing.  p21Waf1/Cip1 deficiency stimulates centriole overduplication. Cell Cycle 24:2899-2902, 2006.
Ghanem L and RA Steinman.  p21Waf1 inhibits granulocytic differentiation of 32Dcl3 cells. Leukemia Research 30:1285-1292, 2006.
Ghanem L and RA Steinman.  A proapoptotic function of p21 in differentiating granulocytes. Leukemia Research 29:1315-1323, 2005.
Steinman RA, Brufsky AM, Oesterreich S. Zoledronic acid effectiveness angainst breast cancer metastases - a role for estrogen in the microenvironment? Breast Cancer Res. 2012 Sep 21;14(5)213 [Epub ahead of print]

STUDENT NEWS


UPCOMING EVENTS
11/27/2017 8:30 AM Molecular Pharmacology Journal Club
Lloyd Harvey


11/30/2017 12:00 PM Pharmacology & Chemical Biology Seminar Series
Jeffrey L. Brodsky, Ph.D.


12/4/2017 8:30 AM Molecular Pharmacology Journal Club
Andrew Lamade


Pharmacology and Chemical Biology Event Calendar

Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Molecular Pharmacology Graduate Program Ranked #2 in Faculty Scholarly Productivity Index


Outcomes:  Time to disseration, last five graduating clasess:  4.5 years, Completion Rate: 84.8%

Ranked #12 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty consecutive years




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