Current Students' Publications

Joshua Lorenz - Guertin

Lorenz-Guertin JM, Wilcox MR, Zhang M, Larsen MB, Pilli J, Schmidt BF, Bruchez MP, Johnson JW, Waggoner AS, Watkins SC, Jacob TC. 2017,  A versatile optical tool for studying synaptic GABAA receptor trafficking. J Cell Sci. 2017 Nov 15;130(22):3933-3945. doi: 10.1242/jcs.205286. Epub 2017 Oct 12. PMID:     29025969 PMCID: PMC5702044

Joshua M. Lorenz-Guertin, Matthew J. Bambino and Tija C. Jacob* 2018, γ2 GABAAR Trafficking and the Consequences of Human Genetic Variation  Front. Cell. Neurosci., 23 August 2018 | https://doi.org/10.3389/fncel.2018.00265

Ravi Patel

Weir MC, Shu ST, Hellwig S, Patel R, Chen L, Tan L, Liu Y, Gray NS, Smithgall TE. 2018, Selective inhibition of the myeloid Src-family kinase Fgr potently suppresses AML cell growth in vitro and in vivo.  ACS Chem Biol. 2018 Jun 15;13(6):1551-1559  PMID: 29763550
 

Nicole Kaminski

Kaminski, N.A. and Wong, E.A. (2018) Differential mRNA expression of nutrient transporters in male and female chickens. Poultry Science, (97)1: 313–318, https://doi.org/10.3382/ps/pex262
 

Ryan Staudt

Moroco JA, Alvarado JJ, Staudt RP, Shi H, Wales TE, Smithgall TE, 2018 Engen JR. Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding. J Mol Biol. 2018 Feb 2;430(3):310-321. doi: 10.1016/j.jmb.2017.12.008. Epub 2017 Dec 16. PMID: 29258818 PMCID: PMC5801098

Victoria Veroli

Tucci P., Veroli V., Señorale M., Marín M. “Escherichia coli: The Leading Model for the Production of Recombinant Proteins” Microbial Models: From Environmental to Industrial Sustainability. Ed. Susana Castro-Sowinski. Springer. 2016. 119-147. Print. 

Munguía B., Teixeira R., Veroli V., Melian E., Saldaña J., Minteguiaga M., Señorale M., Marín M., Domínguez L. “Purification of native M. vogae and H. contortus tubulin by TOG affinity chromatography” Experimental Parasitology. 182:37-44, 2017.

Alex White

Dube, S.; Dube, H.; Green, N.B.; Larsen, E.M.; White, A.; et al. In vivo delivery and activation of masked fluorogenic hydrolase substrates by endogenous hydrolases in C. elegans. ChemBioChem. 2017 Sep 19; 18(18): 1807-1813. doi: 10.1002/cbic.201700278. Epub 2017 Aug 7.PMCID:PMC5605452

Atinuke Dosunmu-Ogunbi

Kulkarni, S., Dolezal, J. M., Wang, H., Jackson, L., Lu, J., Frodey, B. P., Dosunmu-Ogunbi A, Li Y., Fromherz M., Kang A., Santana-Santos L., Benos P., Prochownik, E. V. (2017). Ribosomopathy-like properties of murine and human cancers. PLoS ONE, 12(8)PMCID: PMC5562309
 

Mohan, S., Das, D., Bauer, R. J., Heroux, A., Zalewski, J. K., Heber, S., Dosunmu-Ogunbi A.M., Trakselis M., Hildebrand J., VanDemark, A. P. (2013). Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology. PLoS ONE, 8(12)PMCID: PMC3857177

Joseph Galley

Alvarez RA, Miller MP, Hahn SA, Galley JC, Bauer E, Bachman T, Hu J, Sembrat J, Goncharova D, Mora AL, Rojas M, Goncharova E, Straub AC. Targeting pulmonary endothelial hemoglobin α improves nitric oxide signaling and reverses pulmonary artery endothelial dysfunction. Am J Respir Cell Mol Biol. 2017; Aug 11.
 

Nolan Carew

Smith Sm And Carew Nt*, Milcarek C. Rna Polymerases In Plasma Cells Trav-Ell2 The Beat Of A Different Drum. World J Immunol 2015; 5(3): 99-112 *Co-First Authors
 

Rahaman MM, Nguyen AT, Miller MP, Hahn SA, Sparacino-Watkins C, Jobbagy S, Carew NT, Cantu-Medellin N, Wood KC, Baty CJ, Schopfer FJ, Kelley EE, Gladwin MT, Martin E, Straub AC. Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling. Circ Res. 2017 Jul 7;121(2):137-148. doi: 10.1161/CIRCRESAHA.117.310705. Epub 2017 Jun 5. PMID: 28584062 PMCID: PMC5527687
 

Nelson Am, Carew Nt, Smith Sm, Milcarek C (2018) Rna Splicing In The Transition From B Cells To Antibody Secreting Cells; The Influences Of Ell2, Snrna, And Er Stress. Second Draft Under Review, J. Immun.
 

Lloyd Harvey

Harvey LD, Chan SY. Emerging metabolic therapies in pulmonary arterial hypertension. J Clin Med. 2017;6(4). PubMed PMID: 28375184; PubMed Central PMCID: PMC5406775.

Harvey L, Yin Y, Attarwala IY, Begum G, Deng J, Yan HQ, Dixon CE, Sun D. Administration of DHA reduces ER stress-associated inflammation and alters microglial or macrophage activation in traumatic brain injury. ASN Neuro. 2015;7(6). PubMed PMID: 26685193; PubMed Central PMCID: PMC4710127.

Zonouzi M, Scafidi J, Li P, McEllin B, Edwards J, Dupree JL, Harvey L, Sun D, Hubner CA, Cull-Candy SG, Farrant M, Gallo V. GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nature Neuroscience. 2015;18(5):674-82. Epub 2015/03/31. doi: 10.1038/nn.3990. PubMed PMID: 25821912; PubMed Central PMCID: PMC4459267.

Begum G*, Harvey L*, Dixon CE, Sun D. ER stress and effects of DHA as an ER stress inhibitor. Translational Stroke Research. 2013;4(6):635-42. Epub 2013/12/11. doi: 10.1007/s12975-013-0282-1. PubMed PMID: 24323417; PubMed Central PMCID: PMC3864671. *denotes co-first authorship.

Thong Luong

Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP. Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition. Sci Rep. 2017 Feb 16;7:42604. doi: 10.1038/srep42604. PubMed PMID: 28205616; PubMed Central PMCID: PMC5311997.

Egnatchik RA, Brittain EL, Shah AT, Fares WH, Ford HJ, Monahan K, Kang CJ, Kocurek EG, Zhu S, Luong T, Nguyen TT, Hysinger E, Austin ED, Skala MC, Young JD, Roberts LJ 2nd, Hemnes AR, West J, Fessel JP. Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension. Pulm Circ. 2017 Feb 1;7(1):186-199. doi: 10.1086/690236. eCollection 2017 Mar. PubMed PMID: 28680578; PubMed Central PMCID: PMC5448547.

Nicholas Todd

Huang Y., Todd N., Thathiah A. 2017, The role of GPCRs in neurodegenerative diseases: avenues for therapeutic intervention.  Curr Opin Pharmacol. 2017 Feb;32:96-110. doi: 10.1016/j.coph.2017.02.001. Epub 2017 Mar 10. PMID: 28288370

Regina Schnegelberger

Miki Katuwal, Regina Schnegelberger, Elliott Wityk, Melissa Ruggiero, and Bruno Hagenbuch Establishing the Competitive Counterflow Assay for OATP1B1 and OATP1B3 Published Online:1 Apr 2016Abstract Number:935.5 The FASEB Journal
 

Stephanie Mutchler

Mutchler SM, Straub AC. Compartmentalized nitric oxide signaling in the resistance vasculature. Nitric Oxide. 2015 May 28.
pii:S1089-8603(15)00218-9. doi: 10.1016/j.niox.2015.05.003. PMID: 26028569



Rahaman MM, Reinders FG, Koes D, Nguyen AT, Mutchler SM, Sparacino-Watkins C, Alvarez RA, Miller MP, Cheng D, Chen BB, Jackson EK, Camacho CJ, Straub AC. Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.JBC 2015 PMID:26001785
 

Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE. A molecular signature in the pannexin1 intracellular loop confers channel activation by the alpha1 adrenoreceptor in smooth muscle cells. Sci Signal. (2015) 8; ra17. PMID: 25690012 [PubMed - in process]



Straub AC, Butcher J, Billaud M, Mutchler S, Artamonov M, Nguyen A, Johnson T, Best A, Miller M, Palmer L, Columbus L, Somlyo A, Le T, Isakson B. Hemoglobin alpha/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction. ATVB (2014) 34; 2594-2600. PMID: 25278292 [PubMed - in process] PMCID: PMC4239174 [Available on 2015-12-01]



Billaud M, Lohman AW, Johnstone SR, Biwer LA, Mutchler SM, Isakson BE: Regulation of cellular communication by signaling microdomains in the blood vessel wall. Pharmacol Rev (2014) 66; 513-569. PMID: 24671377 [PubMed - indexed for MEDLINE] PMCID: PMC3973613 [Available on 2015-04-01]



Cechova S, Zeng Q, Billaud M, Mutchler S, Rudy CK, Straub AC, Chi L, Chan FR, Hu J, Griffiths R, Howell NL, Madsen K, Boye J, Palmer LA, Carey RM, Sung SJ, Malakauskas SM, Isakson BE, Le TH: Loss of collectrin, an ACE homologue, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction. Circulation (2013) 128; 1770-1780. PMID: 24048198 [PubMed - indexed for MEDLINE]



Looft-Wilson R, Todd SE, Araj CA, Mutchler SM, Raphael Goodell CA: Alpha1-adrenergic-mediated eNOS phosphorylation in intact arteries. Vascul Pharmacol (2013) 58; 112-117. PMID: 22982055 PMCID: PMC3534816

Braulio Bonilla

Rojas JJ, Sampath P, Bonilla B, Ashley A, Hou W, Byrd D, Thorne SH.Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies. Cell Rep. 2016 Apr 12;15(2):264-73. PMID:  27050526 PMCID: PMC4830920

 

Gregory Buchan

Bilinovich SM, Davis CM, Morris DL, Ray LA, Prokop JW, Buchan GJ, Leeper TC. 2014, The C-terminal domain of SRA1p has a fold more similar to PRP18 than to an RRM and does not directly bind to the SRA1 RNA STR7 region. J Mol Biol. 2014 Apr 17;426(8):1753-65. doi: 10.1016/j.jmb.2014.01.007. Epub 2014 Jan 29. PMID: 24486611