Courtney Andersen studies the role of estrogen receptor-alpha in ovarian cancer.
Chris Barnes investigates the structural details by which transcription factor activity regulates RNA Polymerase II during the universal process of eukaryotic gene expression.
Soma Jobaggy studies nitrated fatty acid pharmacology and the antioxidant response in hypertensive end-organ damage.
Allison Nagle studies growth factor receptor signaling in breast cancer.
Journal Club Schedule

Pharmacology Journal Club

is held on selected Mondays during the Fall and Spring Terms in the Thomas E. Starzl Biomedical Tower, Conference Room 1395 beginning at 8:30 am.


Announcements may also be found on:

 The Department of Pharmacology & Chemical Biology Events Calendar

and on the electronic message board in the main hall on the 13th floor of BSTWR.



Previous Journal Clubs

12/13/2018- 10:45 AM : Song-My Hoang
"ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1"

12/6/2018- 10:45 AM : Greg Buchan
"Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration"

11/29/2018- 10:45 AM : Heidi Schmidt
"Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation"

11/15/2018- 10:45 AM : Joseph Galley
"Targeting p75 neurotrophin receptors ameliorates spinal cord injury-induced detrusor sphincter dyssynergia in mice"

11/8/2018- 10:45 AM : Atinuke Dosunmu-Ogunbi
"Nitrite and nitrate-dependent generation of anti-inflammatory fatty acid nitroalkenes"

11/1/2018- 10:45 AM : Sonja Plasil
"Cytosolic calcium coordinates mitochondrial energy metabolism with presynaptic activity."

10/25/2018- 10:45 AM : BraulioBonilla
"Super-Resolution Imaging of Higher-Order Chromatin Structuresat Different Epigenomic States in Single Mammalian Cells"

10/11/2018- 10:45 AM : Zheqi Li
"Pioglitazone rapidly reduces neuropathic pain through astrocyte and nongenomic PPARg mechanisms"

9/27/2018- 10:45 AM : Nicholas Todd
"shRNA targeting a-synuclein prevents neurodegeneration in a Parkinson’s disease model"

9/20/2018- 10:45 AM : Alex White
"The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction"

9/17/2018- 3:00 PM : Shireen Attaran

Investigating the influence of oxidative stress and the role of Prdx1 in the regulation of lysyl oxidase mediated ECM and collagen remodeling in breast cancer metastasis


8/10/2018- 9:00 AM : Graduate Student Summer Seminar presented by Anastasia Gorelova and Lloyd Harvey

 "New insights into endothelial responses in pulmonary hypertension: potential roles for EBP50 and Aqp1”

Anastasia Gorelova


"A Role for NCOA7 in the Pathogenesis of Pulmonary Hypertension"

Lloyd Harvey

8/3/2018- 9:00 AM : Graduate Student Summer Seminar presented by Andrew Lamade and Nicholas Todd

 "Swopping Regulated Death Programs”

Andrew Lamade


"G protein-coupled receptor kinases modulate Aβ generation"

Nicholas Todd

7/30/2018- 2:00 PM : Nyla Naim

Luminescence activated cyclase allows localized photo and chemical stimulation of cAMP synthesis


7/20/2018- 9:00 AM : Graduate Student Summer Seminar presented by Joshua Lorenz-Guertin and Victoria Veroli

 "Diazepam Accelerates GABAA Receptor Synaptic Exchange and Alters Intracellular Trafficking”

Joshua Lorenz-Guertin


"Kinase domain mutations of PKD as potential drivers of tumorigenesis"

Victoria Veroli

7/13/2018- 9:00 AM : Graduate Student Summer Seminar presented by Braulio Bonilla

 "Rad55 phosphorylation drives interaction with the Shu complex for repair of MMS DNA lesions in S. cerevisiae

Braulio Bonilla


6/29/2018- 9:00 AM : Graduate Student Summer Seminar presented by Stephanie Mutchler and Gregory Buchan

 "Endothelial ENaC modulates vascular reactivity with high salt diet”

Stephanie Mutchler


"NO2-OA and Dendritic Cell Function"

Gregory Buchan

6/15/2018- 9:00 AM : Graduate Student Summer Seminar presented by Song-My Hoang and Alparslan Asan

 "Inhibition of Poly-ADP Ribosylation on Telomere Maintenance by ALT"

Song-My Hoang


"Exploring Electrophilic Fatty Acids Regulate RAD51 Function and Potentiate DNA Damaging Agent Effects on Triple Negative Breast Cancer Cell Growth"

Alparslan Asan

6/11/2018- 10:00 AM : Soma Jobbagy

Impact of Nrf2 signaling on thiol homeostasis and renal physiology


6/8/2018- 9:00 AM : Graduate Student Summer Seminar presented by Ravi Patel and Ryan Staudt

 "The anti-leukemic effect of the tyrosine kinase inhibitor A-419259 is dependent upon inhibition of FLT3-ITD and Src-family kinases”

Ravi Patel


"Defining the structural basis of HIV-1 Nef dimerization in functional complexes with host cell effectors"

Ryan Staudt

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1/10/2019 12:00 PM Pharmacology & Chemical Biology Seminar Series
Mitchell Lazar, M.D., Ph.D.

1/17/2019 12:00 PM Pharmacology & Chemical Biology Seminar Series
Mark Jay Shlomchik, MD, PhD

1/19/2019 12:00 PM Pharmacology & Chemical Biology Seminar Series
Mitchell Lazar, MD, PhD

Pharmacology and Chemical Biology Event Calendar

Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Outcomes:  Time to disseration, last five graduating clasess:  4.5 years, Completion Rate: 84.8%

Ranked #12 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty two consecutive years

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