Courtney Andersen studies the role of estrogen receptor-alpha in ovarian cancer.
Chris Barnes investigates the structural details by which transcription factor activity regulates RNA Polymerase II during the universal process of eukaryotic gene expression.
Soma Jobaggy studies nitrated fatty acid pharmacology and the antioxidant response in hypertensive end-organ damage.
Allison Nagle studies growth factor receptor signaling in breast cancer.
Journal Club Schedule

Pharmacology Journal Club

is held on selected Mondays during the Fall and Spring Terms in the Thomas E. Starzl Biomedical Tower, Conference Room 1395 beginning at 8:30 am.

 

Announcements may also be found on:

 The Department of Pharmacology & Chemical Biology Events Calendar

and on the electronic message board in the main hall on the 13th floor of BSTWR.

 

 

9/17/2018- 3:00 PM : Shireen Attaran

Investigating the influence of oxidative stress and the role of Prdx1 in the regulation of lysyl oxidase mediated ECM and collagen remodeling in breast cancer metastasis


 




Previous Journal Clubs

9/17/2018- 3:00 PM : Shireen Attaran

Investigating the influence of oxidative stress and the role of Prdx1 in the regulation of lysyl oxidase mediated ECM and collagen remodeling in breast cancer metastasis


 


8/10/2018- 9:00 AM : Graduate Student Summer Seminar presented by Anastasia Gorelova and Lloyd Harvey

 "New insights into endothelial responses in pulmonary hypertension: potential roles for EBP50 and Aqp1”

Anastasia Gorelova


and

"A Role for NCOA7 in the Pathogenesis of Pulmonary Hypertension"

Lloyd Harvey



8/3/2018- 9:00 AM : Graduate Student Summer Seminar presented by Andrew Lamade and Nicholas Todd

 "Swopping Regulated Death Programs”

Andrew Lamade

and

"G protein-coupled receptor kinases modulate Aβ generation"

Nicholas Todd



7/30/2018- 2:00 PM : Nyla Naim

Luminescence activated cyclase allows localized photo and chemical stimulation of cAMP synthesis


 


7/20/2018- 9:00 AM : Graduate Student Summer Seminar presented by Joshua Lorenz-Guertin and Victoria Veroli

 "Diazepam Accelerates GABAA Receptor Synaptic Exchange and Alters Intracellular Trafficking”

Joshua Lorenz-Guertin

and

"Kinase domain mutations of PKD as potential drivers of tumorigenesis"

Victoria Veroli



7/13/2018- 9:00 AM : Graduate Student Summer Seminar presented by Braulio Bonilla

 "Rad55 phosphorylation drives interaction with the Shu complex for repair of MMS DNA lesions in S. cerevisiae

Braulio Bonilla

 



6/29/2018- 9:00 AM : Graduate Student Summer Seminar presented by Stephanie Mutchler and Gregory Buchan

 "Endothelial ENaC modulates vascular reactivity with high salt diet”

Stephanie Mutchler

and

"NO2-OA and Dendritic Cell Function"

Gregory Buchan



6/15/2018- 9:00 AM : Graduate Student Summer Seminar presented by Song-My Hoang and Alparslan Asan

 "Inhibition of Poly-ADP Ribosylation on Telomere Maintenance by ALT"

Song-My Hoang

and

"Exploring Electrophilic Fatty Acids Regulate RAD51 Function and Potentiate DNA Damaging Agent Effects on Triple Negative Breast Cancer Cell Growth"

Alparslan Asan



6/11/2018- 10:00 AM : Soma Jobbagy

Impact of Nrf2 signaling on thiol homeostasis and renal physiology
 


 


6/8/2018- 9:00 AM : Graduate Student Summer Seminar presented by Ravi Patel and Ryan Staudt

 "The anti-leukemic effect of the tyrosine kinase inhibitor A-419259 is dependent upon inhibition of FLT3-ITD and Src-family kinases”

Ravi Patel

and

"Defining the structural basis of HIV-1 Nef dimerization in functional complexes with host cell effectors"

Ryan Staudt



6/1/2018- 9:00 AM : Graduate Student Summer Seminar presented by Thong Luong and Zheqi Li

"TBA"

Thong Luong

and

"Hotspot ESR1 mutations drive breast cancer metastasis by context-dependent cell-cell adhesive alteration"

Zheqi Li



5/25/2018- 1:00 PM : Zachary Yochum

TWIST1 Suppresses Apoptosis and Mediates Therapeutic Resistance in Non-Small Cell Lung Cancer
 


 


5/18/2018- 9:00 AM : Graduate Student Summer Seminar presented by Joseph Galley and Atinuke Dosunmu-Ogunbi

 "Regulation of sGC by FoxO Transcription Factors Modulates Vascular Tone”

Joseph Galley

and

"TBA"

Atinuke Dosunmu-Ogunbi



5/11/2018- 9:00 AM : Graduate Student Summer Seminar presented by Alex White and Shireen Attaran

 "Molecular mechanisms regulating PTH receptor signaling and function”

Alex White

and

"Prdx1 regulation of LOX-dependent ECM remodeling in Breast Cancer"

Shireen Attaran



4/23/2018- 12:00 AM : Victoria Veroli
"Allosteric coupling from G protein to the agonist binding pocket in GPCRs"

4/16/2018- 8:30 AM : Nicholas Smith
"Targeting Nonclassical Oncogenes for Therapy in T-ALL"

4/9/2018- 1:00 PM : Rochelle Fletcher

The role of NSAID-induced ER stress and immunomodulation in the suppression of colorectal tumorigenesis


 


4/6/2018- 10:00 AM : Vera Procaccia

The scaffolding protein EBP50 regulates mitochondrial dynamics and redox balance in vascular smooth muscle cells


 


3/19/2018- 8:30 AM : Joseph Galley
"CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli"

3/14/2018- 1:00 PM : Alison Nagle

Credentialing IGF1R pathway activation as a novel therapeutic target in E-cadherin deficient breast cancer


 

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STUDENT NEWS



Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Outcomes:  Time to disseration, last five graduating clasess:  4.5 years, Completion Rate: 84.8%

Ranked #12 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty two consecutive years




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