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Research Description:
Education:
B.S. (Biochemistry), University of California, Riverside, 1974. Ph.D. (Biochemistry), University of California, Riverside, 1978.
Important Publications:
- Iles KE, MM Wright, MP Cole, NE Welty, LB Ware, MA Matthay, FJ Schopfer, PRS Baker, A Agarwal and BA Freeman. Fatty acid transduction of nitric oxide signaling: Nitrolinoleic acid mediates protective effects through regulation of the ERK pathway. Free Radical Biology & Medicine 46:866-875, 2009
- Rudolph V, FJ Schopfer NKH Khoo, TK Rudolph, MP Cole, SR Woodcock, G Bonacci, AL Groeger, F Golin-Bisello, C-S Chen, PRS Baker and BA Freeman. Nitro-fatty acid metabolome: Saturation, desaturation, β-oxidation, and protein adduction. J Biol Chem 284:1461-1473, 2009
- Freeman BA, PRS Baker, FJ Schopfer, SR Woodcock, A Napolitano and M d’Ischia . Nitro-fatty acid formation and signaling. J Biol Chem 283:15515-15519, 2008
- Batthyany C, FJ Schopfer, PR Baker, R Duran, LM Baker, Y Huang, C Cervenansky, BP Branchaud and BA Freeman. Reversible post-translational modification of proteins by nitrated fatty acids in vivo. J Biol Chem 281(29):20450-20463, 2006
- Eiserich JP, S Baldus, M-L Brennan, W Ma, C Zhang, A Tousson, L Castro, AJ Lusis, CR White and BA Freeman. Myeloperoxidase: A leukocyte-derived vascular •NO oxidase. Science 296:2391-2394, 2002
- Radi R, JS Beckman and BA Freeman. Peroxynitrite oxidation of sulfhydryls: The cytotoxic potential of endothelial-derived superoxide and nitric oxide. J Biol Chem 266:4244-4250, 1991
- Beckman JS, TW Beckman, J Chen, PA Marshall and BA Freeman. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci 87:1620-1624, 1990
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