The Levitan lab studies biochemical and electrical signaling that controls neuronal and cardiac function with live cell imaging, electrophysiology and molecular biology. Current projects include in vivo imaging of green fluorescent protein (GFP) constructs in transgenic Drosophila nerve cells and serotonin in mammalian brain slices to determine how patterned electrical activity and synapses control transmitter release. We are also studying remodeling of rhythmic electrical activity in the heart and midbrain dopamine neurons by therapeutically important hormones and drugs. Most recently, multiphoton microscopy is being used to image vesicular accumulation and release of a psychiatric drug in the brain.
Back to Top