Research in Dr. Aizenman's laboratory is directed towards investigating apoptotic and non-apoptotic neuronal cell death processes following the liberation of intracellular zinc.

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Important Publications

Redman, P.Y., K. He, K.A. Hartnett, B.S. jefferson, L. Hu, PlA. Rosenberg, E.S. Levitan and E. Aizenman. Apoptotic surge of potassium currents is mediated by p38 phosphor7lation of Kv2.1. Proc. Natl. Acad. Sci. (U.S.A.) 2007; 104-3568-3573

Redman, P.Y., B.S. Jefferson, C.B. Ziegler, O.V. Mortensen, G.E. Torres, E.S. Levitan and E. Aizenman. A vital role of Kv channels in dopamine transporter-mediated 6-hydroxydopamine neurotoxicity. Neuroscience  2006; 143:1-6.

He, K., J. Huang, C.F. Lagenaur and  E. Aizenman. Methylisothiazolinone, a neurotoxic biocide, disrupts the association of SRC family tyrosine kinases with focal adhesion kinase in developing cortical neurons. J. Pharmacol. Exp. Therap. 2006; 317:1320-1329.

Pal, S., K. Takimoto, E. Aizenman and E.S. Levitan. Apoptotic surface delivery of K(+) channels. Cell Death & Differentiation 2006; 13:661-667.