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Jamie Moroco
Email
jam177@pitt.edu
Education
BS (Biological Sciences, Minor in Chemistry) Carnegie Mellon University, 2007.
Funding Source
Pittsburgh AIDS Research Training Grant (T32) (
2T32AI065380-06
)
Awards Received
American Society for Biochemistry and Molecular Biology (ASBMB) Graduate Student Travel Award for Experimental Biology 2011
Molecular Pharmacology Fellowship (declined funding)
NIH Predoctoral Training Grant (T32) Pittsburgh AIDS Research Training Grant for 2010-2012
Faculty Mentor
Thomas E. Smithgall, PhD
Bridgeside Point II, Room 533
Research
I am interested in the structural dynamics of the Src family kinases and how a better understanding of their mechanisms of activation can lead to more effective and targeted therapies for HIV and cancer.
Publications/Abstracts
Moroco JA
, Alvarado JJ, Yeh JI, and Smithgall TE. Diversity in the Control of individual Src-family kinases by their SH3 domains. April 9-13, 2011. Experimental Biology 2011, Washington, DC. (Abstract)
Alvarado JJ, Betts L,
Moroco JA
, Smithgall TE, Yeh JI.
“Crystal structure of the Src-Family Kinase Hck SH3-SH3-Linker regulatory region supports an SH3-dominant activation mechanism.”
J Biol Chem.
2010, 285:35455-35461
Alvarado JJ, Betts L,
Moroco JA
, Smithgall TE, Yeh JI. “Crystal structure of the Src-Family Kinase Hck SH3-SH3-Linker regulatory region supports an SH3-dominant activation mechanism.”
J Biol Chem.
2010 285: 35455-35461.
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