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Kelly Quesnelle
Photo of Kelly Quesnelle

Email
 kmq1@pitt.edu

Education
BS (Cell and Molecular Biology) University of Michigan, 2003.

Funding Source
 F31 NIH/NIDCR

Awards Received
 F31 Predoctoral National Research Service Award Fellowship, NIH/NIDCR
PhRMA Foundation Predoctoral Fellowship in Pharmacology/Toxicology (declined funding)
T32 Predoctoral Training Grant in Pharmacological Sciences. NIH/NIGMS

Faculty Mentor
Jennifer R. Grandis, MD/FACS
W911 Thomas E. Starzl Biomedical Science Tower


Research

My thesis work in the Grandis Lab centers around the mechanisms of resistance to EGFR-targeted anti-cancer agents. 

Publications/Abstracts
Quesnelle KM and Grandis JR. Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance. Clin Cancer Res. 2011 Sep 15;17(18):5935-44. PMID: 21791633

Yang W, Cai Q, Lui VWY, Everley PA, Kim J, Bhola N, Quesnelle KM, Zetter B, Steen RH, Freeman MR, Grandis JR, Quantitative Proteomics Analysis Reveals Molecular Networks Regulated by Epidermal Growth Factor Receptor Level in Head and Neck Cancer. J Proteome Res. 2010 Jun 4;9(6):3073-82. PMID: 20426488
Quesnelle KM, Grandis JR, Munger KL, Posner MR. (In Press) Molecular Pathology: Head and Neck Cancer in Gelmann E, Sawyers C, Rauscher F (Eds). Molecular Oncology: Causes of Cancer and Targets for Treatment. New York, NY: Cambridge University Press.
Knowles LM, Stabile LP, Egloff AM, Rothstein ME, Thomas SM, Gubish CT, Lerner EC, Seethala RR, Suzuki S, Quesnelle KM, Morgan S, Ferris RL, Grandis JR, Siegfried JM. HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer. Clin Cncer Res. 2009 Jun 1;15(11):3740-50. PMID: 19470725
Ma C, Quesnelle KM, Sparano A, Rao S, Park MS, Cohen MA, Wang Y, Samanta M, Kumar MS, Aziz MU, Naylor TL, Weber BL, Fakharzadeh SS, Weinstein GS, Vachani A, Feldman MD, Brose MS. Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissues. Cancer Biol Ther. 2009 May 9;8(10). PMID: 19276661
Quesnelle KM, Boehm AL, Grandis JR. STAT-mediated EGFR signaling in cancer. J Cell Biochem. Oct 1;102(2):311-9. Review. PMID: 17661350
Sparano A, Quesnelle KM, Kumar MS, Wang Y, Sylvester AJ, Feldman M, Sewell DA, Weinstein GS, Brose MS. Genome-wide profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization. Laryngoscope. 2006 May;116(5):735-41. PMID: 16652080


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