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Shoghag B. Panjarian
Photo of Shoghag B. Panjarian

Email
 sbp9@pitt.edu

Education
MS (Human Physiology), Department of Physiology, Faculty of Medicine, American University of Beirut, Lebanon (2003)
BS (Clinical Laboratory Sciences), Haigazian University, Beirut, Lebanon, 1999.

Awards Received
 Medical School Graduate Department Internal Scholarship, American University of Beirut (2001-2003)

Faculty Mentor
Thomas Smithgal, PhD
Bridgeside Point II, Suite 533


Research

Understanding structure, dynamics and function of deregulated proteins in cancer.

Publications/Abstracts
Choi Y, Seeliger MA, Panjarian SB, Kim H, Deng X, Sim T, Couch B, Koleske AJ, Smithgall TE, Gray NS. N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor. J Biol Chem. 2009 Oct 16;284(42):29005-14.
Panjarian S, Kozhaya L, Arayssi S, Yehia M, Bielawski J, Bielawska A, Usta J, Hannun YA, Obeid LM, Dbaibo GS.. De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation. Prostaglandins Other Lipid Mediat. 2008 Jun;86(1-4):41-8.
Dbaibo GS, Kfoury Y, Darwiche N, Panjarian S, Kozhaya L, Nasr R, Abdallah M, Hermine O, El-Sabban M, de Thé H, Bazarbachi A. Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide synthesis and inhibition of glucosylceramide synthase activity. Haematologica.2007 Jun;92(6):753-62.
Husari AW, Dbaibo GS, Bitar H, Khayat A, Panjarian S, Nasser M, Bitar FF, El-Sabban M, Zaatari G, Mroueh SM. Apoptosis and the activity of ceramide, Bax and Bcl-2 in the lungs of neonatal rats exposed to limited and prolonged hyperoxia.Respir Res
El-Assaad W, Kozhaya L, Araysi S, Panjarian S, Bitar FF, Baz E, El-Sabban ME, Dbaibo GS. Ceramide and glutathione define two independently regulated pathways of cell death initiated by p53 in Molt-4 leukaemia cells. Biochem J. 2003 Dec 15;376(Pt 3):725-32.
Sultan R. and Panjarian S. Propagating fronts in 2D Cr(OH)3 precipitate systems in gelled media. Physica D 157 (2001) 241-250.
1.  Panjarian S and Sultan R. Crystal selection and Liesegang banding in dynamic precipitate systems. Collect. Czech. Commun. (Vol. 66) (2001) 541-554.


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