The Palladino laboratory uses a combined molecular and genetic approach to identify key proteins required for neural maintenance with age and understand the role of these gene products in human disease conditions. The projects in Dr Palladino’s laboratory are directed toward three main goals: 1) discovering and characterizing novel pathways that cause neurodegenerative diseases, 2) understanding the physiological, cellular and molecular dysfunctions that cause neurodegeneration in vivo, and 3) using our animal system in pharmacological screens to identify neuroprotective compounds for the treatment of human neurodegenerative diseases. |
