Courtney Andersen studies the role of estrogen receptor-alpha in ovarian cancer.
Chris Barnes investigates the structural details by which transcription factor activity regulates RNA Polymerase II during the universal process of eukaryotic gene expression.
Soma Jobaggy studies nitrated fatty acid pharmacology and the antioxidant response in hypertensive end-organ damage.
Allison Nagle studies growth factor receptor signaling in breast cancer.
David Osei-Hwedieh studies how hemoglobin mutations such as sickle cell trait affect red blood cell storage integrity and post transfusion survival.
Journal Club Schedule

Pharmacology Journal Club

is held on selected Mondays during the Fall and Spring Terms in the Thomas E. Starzl Biomedical Tower, Conference Room 1395 beginning at 8:30 am.

 

Announcements may also be found on:

 The Department of Pharmacology & Chemical Biology Events Calendar

and on the electronic message board in the main hall on the 13th floor of BSTWR.

 

 

9/21/2015- 8:30 AM : Alison Nagle
"Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis"



Previous Journal Clubs

9/21/2015- 8:30 AM : Alison Nagle
"Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis"

8/7/2015- 9:00 AM : Graduate Student Summer Seminar presented by Andrea Braganza

 "UBE3B is a mitochondria-associated E3 ligase that responds to oxidative stress "
Andrea Braganza




7/24/2015- 9:00 AM : Graduate Student Summer Seminar presented by Mark Weir and Shireen Attaran

"Multi-targeted Tyrosine Kinase Inhibitors Potently Suppress FLT3-ITD+ AML cell growth"
Mark Weir

and

"Establishing the role of Prdx1 in CAF motility and ECM remodeling"
Shireen Attaran



7/17/2015- 9:00 AM : Graduate Student Summer Seminar presented by Alison Nagle and Kyle Knickelbein

"Investigating the functional role of ErbB2 as a mechanosensor in breast cancer"
Alison Nagle

and

"The Role of the Bcl-2 Family Proteins in the Response to Anti-EGFR Antibody Therapy in Colorectal Cancer"
Kyle Knickelbein



7/10/2015- 9:00 AM : Graduate Student Summer Seminar presented by Courtney Andersen and Vera Procaccia

"Targeting estrogen receptor-alpha in high-grade serous ovarian cancer"
Courtney Andersen

and

"EBP50/NHERF1 regulation of oxidative stress through FoxO1-Skp2 in cardiovascular system"
Vera Procaccia



6/26/2015- 9:00 AM : Graduate Student Summer Seminar presented by Nolan Priedigkeit and Rochelle Fletcher

 "Transcriptomic profiling and functional characterization of fusion genes in recurrent ovarian cancer"
Nolan Priedigkeit

and

"Molecular Mechanisms of Death Receptor Signaling in NSAID-mediated chemoprevention”
Rochelle Fletcher



6/19/2015- 9:00 AM : Graduate Student Summer Seminar presented by David Osei-Hwedieh

 "Investigating the effect of Sickle Cell Trait on RBC Storage and Post transfusion Survival"
David Osei-Hwedieh



6/12/2015- 9:00 AM : Graduate Student Summer Seminar presented by Christopher Barnes

"Overcoming challenges in x-ray crystallography: novel techniques for structure determination"
Christopher Barnes




6/5/2015- 9:00 AM : Graduate Student Summer Seminar presented by Gregory Rompala

 "The intergenerational effects of paternal ethanol exposure"
Gregory Rompala




5/29/2015- 9:00 AM : Graduate Student Summer Seminar presented by Nyla Naim and Emily Harrington

 "The Role of cAMP Compartments in Thyroid Cell Proliferation"
Nyla Naim

and

"Targeting the EMT-like Phenotype in Invasive Lobular Carcinoma"
Emily Harrington



5/22/2015- 9:00 AM : Graduate Student Summer Seminar presented by Kenneth Drombosky

 "A test of the Aggregation Hypothesis: The role of protein structure/function in Huntington’s Disease"
Kenneth Drombosky



5/15/2015- 9:00 AM : Graduate Student Summer Seminar presented by Soma Jobbagy and Julia Woodcock

 "Anti-fibrotic Effects of Electrophilic Nitroalkenes"
Soma Jobbagy

and

"Therapeutic Actions of Electrophilic Nitroalkenes in Triple Negative Breast Cancer"
Julia Woodcock



4/27/2015- 8:30 AM : Vera Procaccia
"The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus"

4/20/2015- 8:30 AM : Nolan Priedigkeit
“A novel role of sphingosine kinase-1 in the invasion and angiogenesis of VHL mutant clear cell renal cell carcinoma”

4/13/2015- 8:30 AM : Shireen Attaran
"Functional Characterization of Peroxisome Proliferator-Activated Receptor-β/δ Expression in Colon Cancer"

3/30/2015- 8:30 AM : Noah Peyser
"Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons"

3/23/2015- 12:00 AM : Kenneth Drombosky
"Direct measurement of local oxygen concentration in the bone marrow of live animals"

3/16/2015- 8:30 AM : Soma Jobbagy
"Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner"

3/2/2015- 8:30 AM : Stephanie Mutchler
"15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling
pathways"


2/23/2015- 12:00 AM : Kyle Knickelbein
Ral and Rheb GTPase Activating Proteins Integrate mTOR and GTPase Signaling in Aging, Autophagy, and Tumor Cell Invasion
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STUDENT NEWS


UPCOMING EVENTS
9/21/2015 8:30 AM Molecular Pharmacology Journal Club
Alison Nagle


9/22/2015 3:30 PM Pharmacology & Chemical Biology Seminar Series
Thomas P. Burris, Ph.D.


9/29/2015 3:30 PM Pharmacology and Chemical Biology Seminar Series
Steven Little, PhD


Pharmacology and Chemical Biology Event Calendar




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