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“Modeling human brain structure and function usin...
Pharmacology & Chemical Biology Seminar Series
2/4/2021 - 12:00 PM-1:00 PM
“Modeling human brain structure and function using cerebral organoids”
Madeline Lancaster, Ph.D.
MRC Laboratory of Molecular Biology
Brain organoids are a promising in vitro technology that model developing human brain tissue with remarkable accuracy. We are furthering this method to model later events in neurodevelopment, including neuronal migration and positioning, axon guidance, and neuronal maturation. Recently, we have devised choroid plexus organoids as a model of the human CNS barrier that are also able to secrete cerebrospinal fluid. We are now using these methods to examine human-specific features that set our brains apart.
Contact
Melanie L Hoffner
4123837757