Pharmacology and Chemical Biology Seminar Series

Pharmacology & Chemical Biology Seminar Series
1/21/2021 - 12:00 PM-1:00 PM

Nathaniel Snyder, Ph.D., M.P.H., D.A.B.T.
Associate Professor, Microbiology and Immunology
Associate Professor, Center for Metabolic Disease Research
Temple University, Lewis Katz School of Medicine


Pharmacology & Chemical Biology Seminar Series
1/28/2021 - 12:00 PM-1:00 PM

Nevin Lambert, Ph.D.
Regents’ Professor & Vice Chair for Research
Department of Pharmacology and Toxicology
Augusta University, Medical College of Georgia

Summary: Conventional GPCR-G protein coupling involves a positive allosteric interaction between the agonist-bound state of the receptor and the nucleotide-free state of the G protein. This ternary complex model is the basis for stimulus-response coupling. Recent studies from our lab have uncovered unconventional modes of coupling between GPCRs and G proteins that expand on this model, and suggest that GPCR-G protein interactions are functionally more diverse than previously suspected.

 

Pharmacology & Chemical Biology Seminar Series
2/4/2021 - 12:00 PM-1:00 PM

Madeline Lancaster, Ph.D. 
MRC Laboratory of Molecular Biology


Pharmacology & Chemical Biology Seminar Series
2/11/2021 - 12:00 PM-1:00 PM

Anne Carlson, Ph.D.
Assistant Professor
Department of Biological Sciences
University of Pittsburgh


Pharmacology & Chemical Biology Seminar Series
2/18/2021 - 12:00 PM-1:00 PM

JoAnn Trejo, Ph.D. 
Professor & Vice Chair
Department of Pharmacology
University of California, San Diego


Pharmacology & Chemical Biology Seminar Series
2/25/2021 - 12:00 PM-1:00 PM

Yuanyuan Chen, Ph.D. 
Assistant Professor of Ophthalmology
University of Pittsburgh


Pharmacology & Chemical Biology Seminar Series
3/4/2021 - 12:00 PM-1:00 PM

Jon Lundberg, Ph.D.
Professor
Department of Physiology & Pharmacology
Karolinska Institutet


Pharmacology & Chemical Biology Seminar Series
3/11/2021 - 12:00 PM-1:00 PM

Patrick M. Sung, Ph.D.
Professor of Biochemistry & Structural Biology
Robert A. Welch Distinguished Chair in Biohemistry
The University of Texas Health Science Center at San Antonio


Pharmacology & Chemical Biology Seminar Series
3/18/2021 - 12:00 PM-1:00 PM

Jun Wang , Ph.D. 
Assistant Professor, Dept. of Pathology
NYU Langone Health


Pharmacology & Chemical Biology Seminar Series
3/25/2021 - 12:00 PM-1:00 PM

Gina Sizemore, Ph.D. 
Assistant Professor
Department of Radiation Oncology
The Ohio State University
Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute

Summary: Dr. Sizemore’s research focuses on delineating the key molecular drivers of breast cancer subtype-specific phenotypes with special emphasis on the contributions of the tumorigenic and metastatic tumor microenvironment. In searching for driver pro-metastatic pathways, the Sizemore lab uncovered a mesenchymal-specific receptor tyrosine kinase, platelet derived growth factor receptor-beta (PDGFRβ), which promotes breast cancer metastasis in the brain. Current projects are delving into how tumor-derived PDGFB (the ligand for PDGFRβ) mechanistically promotes metastasis to this distant site and whether pharmacologic disruption of this pathway is therapeutically efficacious for treating women with PDGFB-positive breast cancer.
 

Pharmacology & Chemical Biology Seminar Series
4/1/2021 - 12:00 PM-1:00 PM

Yulong Li, Ph.D.  
Professor
School of Life Sciences
Peking University


Pharmacology & Chemical Biology Seminar Series
4/8/2021 - 12:00 PM-1:00 PM

Jerry Vockley, M.D., Ph.D. 
Division Director, Genetic and Genomic Medicine
Cleveland Family Endowed Chair in Pediatric Research
University of Pittsburgh School of Medicine


Pharmacology & Chemical Biology Seminar Series
4/22/2021 - 12:00 PM-1:00 PM

Dario Alessi, Ph.D.
Professor of Biochemistry
University of Dundee
MRC PPU, School of Life Sciences