Subramaniam Sanker, MSc, PhD

Research Instructor

1301 Thomas Starzl Biomedical Science Tower
200 Lothrop Street
Pittsburgh, PA 15213
Phone: 412-383-8831


BSc (Zoology; minor in Chemistry and Botany), University of Kerala, India
MSc (Life Sciences), University of Hyderabad, India
PhD (Life Sciences; Mechanistic Enzymology), University of Bombay, India
Subramaniam Sanker, MSc, PhD

Journal Articles

Skrypnyk NI, Sanker S, Brilli Skvarca L, Woods C, Chiba T, Patel K, Goldberg ND, McDermott L, Vinson PN, Calcutt MW, Vernetti LA, Vogt A, Huryn DM, Hukriede NA, and de Caestecker  MP. Delayed treatment with PTBA analogues reduces post injury renal fibrosis after kidney injury. Am J Physiol Renal Physiol 310:F705-F716, 2016.
Sanker S, Cirio, MC, Vollmer LL, Goldberg ND, McDermott LA, Hukriede NA, and Vogt A.  Development of high-content assay for kidney progenitor cell expansion in transgenic zebrafish. J BioMol Screen 10:1193-1202, 2013.
Umasankar PK, Sanker S, Thieman JR, Chakraborty S, Wendland B, Tsang M and Traub LM. Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nat Cell Biol 14:488-501, 2012.
Sanker S, Campbell H A and Kent C. Negative cooperativity of substrate binding but not enzyme activity in wild type and mutant forms of CTP: glycerol-3-phosphate cytidylyltransferase. J Biol Chem 276:37922-37928, 2001.
Stevens SS, Sanker S, Kent C and Zuiderweg ERP. Delineation of the allosteric mechanism for a cytidylyltransferase exhibiting negative cooperativity. Nature Structural Biology 8:947-952, 2001.
Sanker S, Chandrasekharan UM, Wilk D, Glynias MJ, Karnik SS and Husain A. Distinct multisite synergistic interactions determine substrate specificities of human chymase and rat chymase-1 for angiotensin II formation and degradation. J Biol Chem. 272: 2963-2968, 1997.
Chandrashekaran UM, Sanker S, Glynias MJ, Karnik SS and Husain A. Angiotensin II-forming activity in a reconstructed ancestral chymase. Science 271: 502-505, 1996.