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Home
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Research
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Straub Lab
Straub Lab
Research
Current Members
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Publications
Nolan Carew
Joseph Galley
Predoctoral Fellow
Heidi Schmidt
Predoctoral Fellow
Adam C. Straub, PhD
Associate Professor
Research Info
Redox signaling mechanisms in the microcirculation.
Nolan Carew
(MED '19)
Advisor
Adam C. Straub, PhD
Nolan Carew
Journal Articles
Rahaman MM, Nguyen AT, Miller MP, Hahn SA, Sparacino-Watkins C, Jobbagy S,
Carew NT
, Cantu-Medellin N, Wood KC, Baty CJ, Schopfer FJ, Kelley EE, Gladwin MT, Martin E, Straub AC. Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling. Circ Res. 2017 Jul 7;121(2):137-148. doi: 10.1161/CIRCRESAHA.117.310705. Epub 2017 Jun 5. PMID: 28584062 PMCID: PMC5527687
Smith Sm And
Carew Nt
*, Milcarek C. Rna Polymerases In Plasma Cells Trav-Ell2 The Beat Of A Different Drum. World J Immunol 2015; 5(3): 99-112 *Co-First Authors
Nelson Am
, Carew Nt, Smith Sm, Milcarek C (2018) Rna Splicing In The Transition From B Cells To Antibody Secreting Cells; The Influences Of Ell2, Snrna, And Er Stress. Second Draft Under Review, J. Immun.
Joseph Galley
Journal Articles
Galley JC,
Durgin BG, Miller MP, Hahn SA, Yuan S, Wood KC, Straub AC. Antagonism of FoxO transcription factors confers loss of soluble guanylate cyclase expression.
Mol Pharmacol.
, 2019 Jun;95(6):629-637.
https://doi.org/10.1124/mol.118.115386
Alvarez RA, Miller MP, Hahn SA,
Galley JC
, Bauer E, Bachman T, Hu J, Sembrat J, Goncharova D, Mora AL, Rojas M, Goncharova E, Straub AC. Targeting pulmonary endothelial hemoglobin α improves nitric oxide signaling and reverses pulmonary artery endothelial dysfunction.
Am J Respir Cell Mol Biol
. 2017; Aug 11.
Adam C. Straub, PhD
Journal Articles
Straub AC
, AW Lohman, M Billaud, SR Johnstone, MY Lee, P Schoppee-Bortz, AK Best, ST Dwyer, L Columbus, B Gaston and BE Isakson. Endothelial cell expression of hemoglobin alpha regulates nitric oxide signaling. Nature 491:473-477, 2012.
Straub AC
, M Billaud, SR Johnstone, AK Best, S Yemen, ST Dwyer, R Looft-Wilson, JJ Lysiak, B Gaston, LA Palmer and BE Isakson. Compartmentalized connexin 43 S-nitrosylation/denitrosylation regulates heterocellular communication in the vessel wall. Arterioscler Thromb Vasc Biol 31:399-407, 2011.
Billaud M, AW Lohman,
AC Straub
, R Looft-Wilson, SR Johnstone, CA Araj, AK Best, F Chekeni, K Ravichandran, S Penuela, D Laird and BE Isakson. Pannexin 1 regulates alpha 1-adrenergic receptor-mediated vasoconstriction. Circ Res 109:80-85, 2011.
Heberlein K,
AC Straub
, AK Best, RC Looft-Wilson and BE Isakson. Plasminogen activator inhibitor-1 can regulate myoendothelial junction formation. Circ Res 106:1092-1102, 2010.
Straub AC
, KA Clark, MA Ross, AG Chandra, S Li, X Gao, PJ Pagano, DB Stolz and A Barchowsky. Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH-oxidase generated superoxide. J Clin Invest 118:3980-3989, 2008.
Straub AC
, DB Stolz, MA Ross, A Hernandez-Zavala, NV Soucy, LR Klei and A Barchowsky. Arsenic stimulates sinusoidal endothelial cell capillarization and vessel remodeling in mouse liver. Hepatology 45:205-212, 2007.