Current Students' Publications

Braulio Bonilla

Journal Articles

Rojas JJ, Sampath P, Bonilla B, Ashley A, Hou W, Byrd D, Thorne SH.Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies. Cell Rep. 2016 Apr 12;15(2):264-73. PMID:  27050526 PMCID: PMC4830920

 

Gregory Buchan

Journal Articles

Bilinovich SM, Davis CM, Morris DL, Ray LA, Prokop JW, Buchan GJ, Leeper TC. 2014, The C-terminal domain of SRA1p has a fold more similar to PRP18 than to an RRM and does not directly bind to the SRA1 RNA STR7 region. J Mol Biol. 2014 Apr 17;426(8):1753-65. doi: 10.1016/j.jmb.2014.01.007. Epub 2014 Jan 29. PMID: 24486611

Atinuke Dosunmu-Ogunbi

Journal Articles

Kulkarni, S., Dolezal, J. M., Wang, H., Jackson, L., Lu, J., Frodey, B. P., Dosunmu-Ogunbi A, Li Y., Fromherz M., Kang A., Santana-Santos L., Benos P., Prochownik, E. V. (2017). Ribosomopathy-like properties of murine and human cancers. PLoS ONE12(8)PMCID: PMC5562309
 

Mohan, S., Das, D., Bauer, R. J., Heroux, A., Zalewski, J. K., Heber, S., Dosunmu-Ogunbi A.M., Trakselis M., Hildebrand J., VanDemark, A. P. (2013). Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology. PLoS ONE8(12)PMCID: PMC3857177


Joseph Galley

Journal Articles

Alvarez RA, Miller MP, Hahn SA, Galley JC, Bauer E, Bachman T, Hu J, Sembrat J, Goncharova D, Mora AL, Rojas M, Goncharova E, Straub AC. Targeting pulmonary endothelial hemoglobin α improves nitric oxide signaling and reverses pulmonary artery endothelial dysfunction. Am J Respir Cell Mol Biol. 2017; Aug 11.
 

Lloyd Harvey

Journal Articles

Harvey LD, Chan SY. Emerging metabolic therapies in pulmonary arterial hypertension. J Clin Med. 2017;6(4). PubMed PMID: 28375184; PubMed Central PMCID: PMC5406775.

Harvey L, Yin Y, Attarwala IY, Begum G, Deng J, Yan HQ, Dixon CE, Sun D. Administration of DHA reduces ER stress-associated inflammation and alters microglial or macrophage activation in traumatic brain injury. ASN Neuro. 2015;7(6). PubMed PMID: 26685193; PubMed Central PMCID: PMC4710127.

Zonouzi M, Scafidi J, Li P, McEllin B, Edwards J, Dupree JL, Harvey L, Sun D, Hubner CA, Cull-Candy SG, Farrant M, Gallo V. GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nature Neuroscience. 2015;18(5):674-82. Epub 2015/03/31. doi: 10.1038/nn.3990. PubMed PMID: 25821912; PubMed Central PMCID: PMC4459267.

Begum G*, Harvey L*, Dixon CE, Sun D. ER stress and effects of DHA as an ER stress inhibitor. Translational Stroke Research. 2013;4(6):635-42. Epub 2013/12/11. doi: 10.1007/s12975-013-0282-1. PubMed PMID: 24323417; PubMed Central PMCID: PMC3864671. *denotes co-first authorship.


Nicole Kaminski

Journal Articles

Kaminski, N.A. and Wong, E.A. (2018) Differential mRNA expression of nutrient transporters in male and female chickens. Poultry Science, (97)1: 313–318, https://doi.org/10.3382/ps/pex262
 

Joshua Lorenz - Guertin

Journal Articles

Joshua M. Lorenz-Guertin, Matthew J. Bambino and Tija C. Jacob* 2018, γ2 GABAAR Trafficking and the Consequences of Human Genetic Variation  Front. Cell. Neurosci., 23 August 2018 | https://doi.org/10.3389/fncel.2018.00265
Ye J, Das S, Roy A, Wei W, Huang H, Lorenz-Guertin JM, Zhang Z, Xu Q, Jacob TC, Wang B, Sun D, Wang QJ. Ischemic injury-induced CaMKIIδ and CaMKIIγ confer neuroprotection through the NF-κB signaling pathway. (June 2018 accepted in Mol Neurobiol).
Brady ML, Pilli J, Lorenz-Guertin JM, Das S, Moon CE, Graff N, Jacob TC. 2018, Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology. 2018 Jan;128:324-339. doi: 10.1016/j.neuropharm.2017.10.022. Epub 2017 Oct 23. PMID: 29074304 PMCID: PMC5739058
Lorenz-Guertin JM, Wilcox MR, Zhang M, Larsen MB, Pilli J, Schmidt BF, Bruchez MP, Johnson JW, Waggoner AS, Watkins SC, Jacob TC. 2017,  A versatile optical tool for studying synaptic GABAA receptor trafficking. J Cell Sci. 2017 Nov 15;130(22):3933-3945. doi: 10.1242/jcs.205286. Epub 2017 Oct 12. PMID:     29025969 PMCID: PMC5702044
Lorenz-Guertin JM, Jacob TC.  2018, GABA type a receptor trafficking and the architecture of synaptic inhibition. Dev Neurobiol. 2018 Mar;78(3):238-270. doi: 10.1002/dneu.22536. Epub 2017 Sep 19. Review. PMID 28901728

Thong Luong

Journal Articles

Egnatchik RA, Brittain EL, Shah AT, Fares WH, Ford HJ, Monahan K, Kang CJ, Kocurek EG, Zhu S, Luong T, Nguyen TT, Hysinger E, Austin ED, Skala MC, Young JD, Roberts LJ 2nd, Hemnes AR, West J, Fessel JP. Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension. Pulm Circ. 2017 Feb 1;7(1):186-199. doi: 10.1086/690236. eCollection 2017 Mar. PubMed PMID: 28680578; PubMed Central PMCID: PMC5448547.

Hardeman KN, Peng C, Paudel BB, Meyer CT, Luong T, Tyson DR, Young JD, Quaranta V, Fessel JP. Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition. Sci Rep. 2017 Feb 16;7:42604. doi: 10.1038/srep42604. PubMed PMID: 28205616; PubMed Central PMCID: PMC5311997.


Ravi Patel

Journal Articles

Weir MC, Shu ST, Hellwig S, Patel R, Chen L, Tan L, Liu Y, Gray NS, Smithgall TE. 2018, Selective inhibition of the myeloid Src-family kinase Fgr potently suppresses AML cell growth in vitro and in vivo.  ACS Chem Biol. 2018 Jun 15;13(6):1551-1559  PMID: 29763550
 

Regina Schnegelberger

Journal Articles

Miki Katuwal, Regina Schnegelberger, Elliott Wityk, Melissa Ruggiero, and Bruno Hagenbuch Establishing the Competitive Counterflow Assay for OATP1B1 and OATP1B3 Published Online:1 Apr 2016Abstract Number:935.5 The FASEB Journal
 

Ryan Staudt

Journal Articles

Moroco JA, Alvarado JJ, Staudt RP, Shi H, Wales TE, Smithgall TE, 2018 Engen JR. Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding. J Mol Biol. 2018 Feb 2;430(3):310-321. doi: 10.1016/j.jmb.2017.12.008. Epub 2017 Dec 16. PMID: 29258818 PMCID: PMC5801098

Nicholas Todd

Journal Articles

Huang Y., Todd N., Thathiah A. 2017, The role of GPCRs in neurodegenerative diseases: avenues for therapeutic intervention.  Curr Opin Pharmacol. 2017 Feb;32:96-110. doi: 10.1016/j.coph.2017.02.001. Epub 2017 Mar 10. PMID: 28288370

Alex White

Journal Articles

Dube, S.; Dube, H.; Green, N.B.; Larsen, E.M.; White, A.; et al. In vivo delivery and activation of masked fluorogenic hydrolase substrates by endogenous hydrolases in C. elegans. ChemBioChem. 2017 Sep 19; 18(18): 1807-1813. doi: 10.1002/cbic.201700278. Epub 2017 Aug 7.PMCID:PMC5605452

Student News



Events

Molecular Pharmacology Journal Club
Victoria Heinrich
Thomas E. Starzl Biomedical Science Tower
1395 Conference Room

Recent Publications

Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Outcomes: 

Time to dissertation Defense
, last five graduating classes:  4.6 years, Completion Rate: 86.49%

First Author Publications (All students, past 5 year mean):  2.03;   Total Publications: 5.10

F-series Grants (F30/F31) (All Students, past 5 year mean):  12/34 (35%) 


Ranked #9 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty-four consecutive years