Pharmacology and Chemical Biology Seminar Series

Pharmacology & Chemical Biology Seminar Series
3/4/2021 - 12:00 PM-1:00 PM

Jon Lundberg, Ph.D.
Professor
Department of Physiology & Pharmacology
Karolinska Institutet

Topic: Oral bacteria are generally associated with diseases ranging from caries and bad breath to periodontitis, cardiovascular disease and cancer. Here I discuss more recent findings instead implying a symbiotic relationship between oral nitrate-reducing bacteria and the host in systemic nitric oxide (NO) homeostasis for regulation of cardiovascular and metabolic function.

 

Pharmacology & Chemical Biology Seminar Series
3/11/2021 - 12:00 PM-1:00 PM

Patrick M. Sung, Ph.D.
Professor of Biochemistry & Structural Biology
Robert A. Welch Distinguished Chair in Biohemistry
The University of Texas Health Science Center at San Antonio


Pharmacology & Chemical Biology Seminar Series
3/18/2021 - 12:00 PM-1:00 PM

Jun Wang , Ph.D. 
Assistant Professor, Dept. of Pathology
NYU Langone Health


Pharmacology & Chemical Biology Seminar Series
3/25/2021 - 12:00 PM-1:00 PM

Gina Sizemore, Ph.D. 
Assistant Professor
Department of Radiation Oncology
The Ohio State University
Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute

Summary: Dr. Sizemore’s research focuses on delineating the key molecular drivers of breast cancer subtype-specific phenotypes with special emphasis on the contributions of the tumorigenic and metastatic tumor microenvironment. In searching for driver pro-metastatic pathways, the Sizemore lab uncovered a mesenchymal-specific receptor tyrosine kinase, platelet derived growth factor receptor-beta (PDGFRβ), which promotes breast cancer metastasis in the brain. Current projects are delving into how tumor-derived PDGFB (the ligand for PDGFRβ) mechanistically promotes metastasis to this distant site and whether pharmacologic disruption of this pathway is therapeutically efficacious for treating women with PDGFB-positive breast cancer.
 

Pharmacology & Chemical Biology Seminar Series
4/1/2021 - 12:00 PM-1:00 PM

Yulong Li, Ph.D.  
Professor
School of Life Sciences
Peking University


Pharmacology & Chemical Biology Seminar Series
4/8/2021 - 12:00 PM-1:00 PM

Jerry Vockley, M.D., Ph.D. 
Division Director, Genetic and Genomic Medicine
Cleveland Family Endowed Chair in Pediatric Research
University of Pittsburgh School of Medicine


Pharmacology & Chemical Biology Seminar Series
4/22/2021 - 12:00 PM-1:00 PM

Dario Alessi, Ph.D.
Professor of Biochemistry
University of Dundee
MRC PPU, School of Life Sciences