Kyle Knickelbein

Graduate Student Researcher

Hillman Cancer Center Research Pavillion 2.43
5117 Centre Avenue
Pittsburgh, PA 15213


BS, Bioengineering with Chemical Engineering Option ( Biology Minor), The Pennsylvania State University, 2011
Kyle Knickelbein

Journal Articles

Li, L., Knickelbein, K., Zhang, L., Wang, J., Obrinske, M., Ma, G.Z., Zhang, L.M., Bitterman, L. and Du, W. (2015) Amphiphilic sugar poly (orthoesters) as ph-responsive nanoscopic assemblies for acidity-enhanced drug delivery and cell killing. Chemical Communications 51 :13078-13081. PMID: 26096366
Knickelbein K, Zhang L. Mutant KRAS as a critical determinant of the therapeutic response of colorectal cancer. Genes Dis. 2015 Mar;2(1):4-12. PMID: 25815366 [PubMed] PMCID:  PMC4372129

Fu L, Li L, Wang J, Knickelbein K, Zhang L, Milligan I, Xu Y, O'Hara K, Bitterman L, Du W. Synthesis of clickable amphiphilic polysaccharides as nanoscopic assemblies. Chem Commun (Camb). 2014 Oct 28;50(84):12742-5. doi: 10.1039/c4cc06343k. PubMed PMID: 25204678.

Sun J, Knickelbein K, He K, Chen D, Dudgeon C, Shu Y, Yu J, Zhang L. Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells. Mol Cancer Ther. 2014 May;13(5):1298-308. doi: 10.1158/1535-7163.MCT-13-0846. Epub 2014 Feb 21. PubMed PMID: 24563542; PubMed Central PMCID: PMC4013266

Awards and Honors

Sponsored Research

Cotswold Fund Award