Skip to Main Content
Pitt Home
Find People
School of Medicine
Toggle navigation
Skip Navigation Links
Home
About
Leadership
Mission
Department Statistics
Building Information
Thomas E. Starzl BST
Biomedical Science Tower 3
Conference Rooms
BSTWR E1347 - Wingard/Lazo Conference Room
BSTWR 1395
Shops
Cell Biology/Pharmacology Machine Shop
Directory
Primary Faculty
Secondary Faculty
Graduate Students
Fellows
Administrative Staff
Research Staff
Adjunct Faculty
Department Alumni
Research
Research Areas
Labs
Equipment
Non-PC&B Personnel Core Facilities Access Request
Funding Opportunities
Faculty Development Program
Responsible Conduct of Research
Education
Molecular Pharmacology Graduate Program
Current Students
Current Student Roster
Student Publications
Diversity, Accessibility, and Counseling
Student Awards
MPGP News
Student Poster and Presentation Resources
Prospective Students
Welcome from the Director
Research Opportunities
PhD Track
MD/PhD Track
Financial Aid
Graduate Faculty
Admin Staff
Graduate Courses
Lab Rotations
Events
Grad Student Event Calendar
Graduate Student Event Schedule
Alumni/Career Development
Alumni
Alumni Contacts
Molecular Pharmacology Facebook Group
Molecular Pharmacology Student-Alumni Network (LinkedIn)
SOM Graduate Studies - Career and Professional Development
Executive Committee
Student Testimonials
IBGP
Funding Opportunities
NIH T32 Training Grant
Outcomes
Predoctoral Fellowship
Admissions
Student Handbook & General Timeline
Links
Useful Links
School of Medicine
PubMed
Remote Resources
Biomedical Masters Program
Undergraduate Research
Summer Fellowships
Lab Rotations
Graduate Fellowships
News
Events
Calendar
Seminar Series
Links
Contact
Opportunities
Department
PORtal
Computer Resources Access Request
IT-Equipment-Facilities Support Request
Poster Requests
Reservation Calendars
Badge Access Request
Home
>
Events
>
Calendar
>
“The Opportunities and Challenges of Developing No...
Pharmacology & Chemical Biology Seminar Series
2/17/2022 - 12:00 PM-1:00 PM
“The Opportunities and Challenges of Developing Novel Therapeutics for Parkinson’s Disease”
Warren Hirst, PhD
Senior Director
Biogen
Over the past 20 years there has been considerable progress in the understanding the genetic basis of Parkinson’s disease (PD). The genetics have complemented human pathology and we now have an increased knowledge of the disease pathophysiology with lysosomal dysfunction, endosomal trafficking, mitochondrial quality control and immune response being the predominant pathways linked to PD. This has provided us with well validated therapeutic targets, including a-synuclein, LRRK2, GBA and Parkin. I will present and discuss the opportunities and challenges of developing novel therapeutics to these targets and how we are linking familial and sporadic forms of the disease in preclinical research and in clinical development.
Contact
Melanie Hoffner