Joshua Lorenz - Guertin

Predoctoral Fellow

W1308 Thomas E. Starzl Biomedical Science Tower
Pittsburgh, PA 15260

Education

BS, Biological Sciences, Grand Valley State University, 2010

 
Joshua Lorenz - Guertin

Labs

Joshua M. Lorenz-Guertin, Matthew J. Bambino and Tija C. Jacob* 2018, γ2 GABAAR Trafficking and the Consequences of Human Genetic Variation  Front. Cell. Neurosci., 23 August 2018 | https://doi.org/10.3389/fncel.2018.00265
Ye J, Das S, Roy A, Wei W, Huang H, Lorenz-Guertin JM, Zhang Z, Xu Q, Jacob TC, Wang B, Sun D, Wang QJ. Ischemic injury-induced CaMKIIδ and CaMKIIγ confer neuroprotection through the NF-κB signaling pathway. (June 2018 accepted in Mol Neurobiol).
Brady ML, Pilli J, Lorenz-Guertin JM, Das S, Moon CE, Graff N, Jacob TC. 2018, Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology. 2018 Jan;128:324-339. doi: 10.1016/j.neuropharm.2017.10.022. Epub 2017 Oct 23. PMID: 29074304 PMCID: PMC5739058
Lorenz-Guertin JM, Wilcox MR, Zhang M, Larsen MB, Pilli J, Schmidt BF, Bruchez MP, Johnson JW, Waggoner AS, Watkins SC, Jacob TC. 2017,  A versatile optical tool for studying synaptic GABAA receptor trafficking. J Cell Sci. 2017 Nov 15;130(22):3933-3945. doi: 10.1242/jcs.205286. Epub 2017 Oct 12. PMID:     29025969 PMCID: PMC5702044
Lorenz-Guertin JM, Jacob TC.  2018, GABA type a receptor trafficking and the architecture of synaptic inhibition. Dev Neurobiol. 2018 Mar;78(3):238-270. doi: 10.1002/dneu.22536. Epub 2017 Sep 19. Review. PMID 28901728

Awards and Honors

William C. de Groat Neuropharmacology Department Fellowship

 

Sponsored Research

Diazepam induces synaptic GABA type A receptor plasticity via multiple trafficking mechanisms - 9/1/2018 - 2/28/2020
NIH - F31 MH117839-01

Student News




Recent Publications

Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Outcomes: 

Time to dissertation Defense
, last five graduating classes:  4.6 years, Completion Rate: 86.49%

First Author Publications (All students, past 5 year mean):  2.03;   Total Publications: 5.10

F-series Grants (F30/F31) (All Students, past 5 year mean):  12/34 (35%) 


Ranked #9 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty-four consecutive years