Department of Medicine
Faculty Profiles by Division

Division of Renal-Electrolyte

Faculty Profiles
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photo Youko Ikeda, PhD

Renal-Electrolyte

Assistant Professor of Medicine

Email: yoi4@pitt.edu

Phone: 412-383-5939
Contact
Office: 3550 Terrace Street
A1207 Scaife Hall
Pittsburgh, PA 15261
 
Phone: 412-383-5939
Fax:
E-mail: yoi4@pitt.edu
Education and Training
Education
Ph.D. in Urology/Cell Physiology, University College London, University of London, 2006
B.Sc. in Biochemistry, Imperial College London, University of London, 2001
Research Interest
Dr. Ikeda’s research interests focus on furthering the understanding of the various cellular mechanisms that regulate urinary bladder contractile and storage functions, as well as determining the consequences of neurogenic injury, chemical cystitis and ionizing radiation exposure to the lower urinary tract to elucidate novel therapeutic agents.
Publications
For my complete bibliography, Click Here.
Selected Publications:
Kanai, A., Zabbarova, I., Oefelein, M., Radziszewski, P., Ikeda, Y., Andersson, K.E. Mechanisms of action of botulinum neurotoxins, ß3-adrenergic receptor agonists, and PDE5 inhibitors in modulating detrusor function in overactive bladders: ICI-RS 2011. Neurourology and urodynamics. 2012; 31(3): 300-8.
Kanai, A., Zabbarova, I., Ikeda, Y., Yoshimura, N., Birder, L., Hanna-Mitchell, A., de Groat, W. Sophisticated models and methods for studying neurogenic bladder dysfunction. Neurourology and urodynamics. 2011; 30(5): 658-67.
Kanai, A., Wyndaele, J.J,, Andersson, K.E., Fry, C., Ikeda, Y., Zabbarova, I., De Wacher, S. Researching bladder afferents-determining the effects of ß(3) -adrenergic receptor agonists and botulinum toxin type-A. Neurourology and urodynamtics. 2011; 30(5): 684-91.
Ikeda, Y., Birder, L., Buffington, C., Roppolo, J., Kanai, A. Mucosal muscarinic receptors enhance bladder activity in cats with feline interstitial cystitis. The Journal of urology. 2009; 181(3): 1415-22.
Sui, G.P., Wu, C., Roosen, A., Ikeda, Y., Kanai, A.J., Fry, C.H. Modulation of bladder myofibroblast activity: implications for bladder function. American Journal of physiology - Renal physiology. 2008; 295(3): F688-97.
Ikeda, Y., Fry, C., Hayashi, F., Stolz, D., Griffiths, D., Kanai, A. Role of gap junctions in spontaneous activity of the rat bladder. American Journal of physiology - renal physiology. 2007; 295(3): F1018-25.
Kanai, A., Roppolo, J., Ikeda, Y., Zabbarova, I., Tai, C., Birder, L., Griffiths, D., de Groat, W., Fry, C. Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists. American Journal of physiology - Renal physiology. 2007; 292(3): F1065-72.
Blake-James, B.T., Rashidian, A., Ikeda, Y., Emberton, M. The role of anticholinergics in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: a systematic review and meta-analysis. BJU International. 2007; 99(1): 85-96.
Fry, C.H., Ikeda, Y., Harvey, R., Wu, C., Sui, G.P. Control of bladder function by peripheral nerves: avenues for novel drug targets. Urology. 2004; 63(3suppl1): 24-31.
Fry, C.H., Hussain, M., McCarthy, C., Ikeda, Y., Sui, G.P., Wu,C. Recent advances in detrusor muscle function. Scandinavian Journal of Urology and nephrology. 2004; 215: 20-5.
Sponsored Research/Activities
Title: Enhancing Recovery of SCI-Induced Bladder Dysfunction Using Small Molecules
Role: Co-Principal Investigator
Funding Agency: Department of Defense
Grant Number: RES
Start Year: 2018
End Year: 2021
Title: PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse Bladders
Role: Collaborator
Funding Agency: National Institute of Health
Grant Number: R01 R01DK098361
Start Year: 2020
End Year: 2025
Title: Contribution of Stress Induced Autonomic and Urothelial Dysregulation to IC/BPS
Role: Faculty Collaborator
Funding Agency: National Institute of Diabetes, Digestive, & Kidney Disease
Grant Number: R01 DK115476
Start Year: 2018
End Year: 2023
Title: Bladder Mucosal Dysfunction During Aging
Role: Faculty Collaborator
Funding Agency: National Institute of Aging
Grant Number: R01 AG056944
Start Year: 2018
End Year: 2023

Division Websites

Cardiology

Endocrinology and Metabolism

Gastroenterology, Hepatology and Nutrition

General Internal Medicine

Geriatric Medicine
Hematology/Oncology

Infectious Diseases

Pulmonary, Allergy and Critical Care Medicine

Renal-Electrolyte

Rheumatology and Clinical Immunology

Contact

Department of Medicine
1218 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
Email:  chairoff@pitt.edu
Phone:  412-648-9636
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