Skip to Main Content

Current Students' Publications

Olayemi Akinyele

Journal Articles

Smith, Michael and Yadav, Swara and Akinyele, Olayemi and Pels, Nana Adjoa and Horton, Daniel and Alsultan, Nashwah and Borns, Andrea and Cousin, Carolyn and Dixon, Freddie and Mann, Victoria H. and Lee, Clarence and Brindley, Paul J. and El-Sayed, Najib M. and Bridger, Joanna M. and Knight, Matty. PIWI silencing mechanism involving the retrotransposon nimbus orchestrates resistance to infection with Schistosoma mansoni in the snail vector, Biomphalaria glabrata. bioRxiv. 2021. doi:https://doi.org/10.1101/2021.01.12.426235

Wenxi An

Journal Articles

Reyes C, An W, Mo L, St Croix C, Shiva S. Nitrite inhibits mitofusin-1 degradation to attenuate vascular smooth muscle proliferation.  In Preparation (to be submitted by July 31, 2021 to Atherosclerosis, Thrombosis and Vascular Biology)

Dennis Braden

Journal Articles

Zhu D, Dai W, Srinivasan P, McClellan H, Braden D, Allee-Munoz A, Hurtado PAG, Miller LH, Duffy PE. Characterization of AMA1-RON2L complex with native gel electrophoresis and capillary isoelectric focusing  Electrophoresis. 2021 Oct 22. doi: 10.1002/elps.202000365. Online ahead of print. PMID: 34679212

Caitlyn Chapman

Journal Articles

Garrudo FFF, Mikael PE, Xia K, Silva JC, Ouyang Y, Chapman CA, Hoffman PR, Yu Y, Han X, Rodrigues CAV, Cabral JMS, Morgado J, Ferreira FC, Linhardt RJ. The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells. Biochimie. 2021 Mar;182:61-72. doi: 10.1016/j.biochi.2021.01.001. Epub: 2021 Jan 7.
Garrudo FFF, Mikael PE, Xia K, Silva JC, Ouyang Y, Chapman CA, Hoffman PR, Yu Y, Han X, Rodrigues CAV, Cabral JMS, Morgado J, Ferreira FC, Linhardt RJ. The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells. Biochimie. 2021 Mar;182:61-72. doi: 10.1016/j.biochi.2021.01.001. Epub: 2021 Jan 7.
Garrudo FFF, Mikael PE, Rodrigues CAV, Udangawa RW, Paradiso P, Chapman CA, Hoffman P, Colaço R, Cabral JMS, Morgado J, Linhardt RJ, Ferreira FC. Polyaniline-polycaprolactone fibers for neural applications: Electroconductivity enhanced by pseudo-doping. Mater Sci Eng C Mater Biol Appl. 2021 Jan;120:111680. doi: 10.1016/j.msec.2020.111680. Epub: 2020 Nov 4.
Garrudo FFF, Mikael PE, Rodrigues CAV, Udangawa RW, Paradiso P, Chapman CA, Hoffman P, Colaço R, Cabral JMS, Morgado J, Linhardt RJ, Ferreira FC. Polyaniline-polycaprolactone fibers for neural applications: Electroconductivity enhanced by pseudo-doping. Mater Sci Eng C Mater Biol Appl. 2021 Jan;120:111680. doi: 10.1016/j.msec.2020.111680. Epub: 2020 Nov 4
Bhattacharya S, Roy I, Tice A, Chapman C, Udangawa R, Chakrapani V, Plawsky JL, Linhardt RJ. High-Conductivity and High-Capacitance Electrospun Fibers for Supercapacitor Applications. ACS Appl Mater Interfaces. 2020 Apr 29;12(17):19369-19376. doi: 10.1021/acsami.9b21696. Epub: 2020 Apr 20.
Bhattacharya S, Roy I, Tice A, Chapman C, Udangawa R, Chakrapani V, Plawsky JL, Linhardt RJ. High-Capacitance Electrospun Fibers for Supercapacitor Applications. ACS Appl Mater Interfaces. 2020 Apr 29;12(17):19369-19376. doi: 10.1021/acsami.9b21696. Epub: 2020 Apr 20.
Garrudo FFF, Udangawa RN, Hoffman PR, Sordini L, Chapman CA, Mikael PE, Ferreira FA, Silva JC, Rodrigues CAV, Cabral JMS, Morgado JMF, Ferreira FC, Linhardt RJ. POLYBENZIMIDAZOLE NANOFIBERS FOR NEURAL STEM CELL CULTURE. Mater Today Chem. 2019 Dec;14. doi: 10.1016/j.mtchem.2019.08.004. Epub: 2019 Sep 27.
Garrudo, F.F.F.; Udangawa, R.N.; Hoffman, P.R.; Sordini, L.; Chapman, C.A.; Mikael, P.E.; Ferreira, F.A.; Silva, J.C.; Rodrigues, C.A.V.; Cabral, J.M.S.; Morgado, J.M.F.; Ferreira, F.C.; Linhardt, R.J.Polybenzimidazole nanofibers for neural stem cell culture. Materials Today Chemistry. December 2019;14. doi: 10.1016/j.mtchem.2019.08.004.

Fabliha Chowdhury

Journal Articles

Wu, L.; Li, X.; Lin, Q.; Chowdhury, F.; Mazumder, M.H.; Du, W.FANCD2 and HES1 suppress inflammation-induced PPAR? to prevent haematopoietic stem cell exhaustion. British Journal of Haematology. February 2021;192(3):652-663. doi: 10.1111/bjh.17230.
Ahmed, T.; Archie, S.R.; Faruk, A.; Chowdhury, F.A.; Shoyaib, A.A.; Ahsan, C.R.Evaluation of the anti-inflammatory activities of diclofenac sodium, prednisolone and atorvastatin in combination with ascorbic acid. Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. 2020;19(3):291-301. doi: 10.2174/1871523018666190514112048.
Wu L, Li X, Lin Q, Chowdhury F, Mazumder MH, Du W. (2020). FANCD2 and HES1suppress inflammation-induced PPAR? to prevent haematopoietic stem cell exhaustion. Br J Haematol. doi: 10.1111/bjh.17230. PMID: 33222180.
Wu, L.; Lin, Q.; Ma, Z.; Chowdhury, F.A.; Mazumder, M.H.H.; Du, W.Mesenchymal PGD2 activates an ILC2-Treg axis to promote proliferation of normal and malignant HSPCs. Leukemia. 1 November 2020;34(11):3028-3041. doi: 10.1038/s41375-020-0843-8.
Ma, Z.; Xu, J.; Wu, L.; Wang, J.; Lin, Q.; Chowdhury, F.A.; Mazumder, M.H.H.; Hu, G.; Li, X.; Du, W.Hes1 deficiency causes hematopoietic stem cell exhaustion. Stem Cells. 1 June 2020;38(6):756-768. doi: 10.1002/stem.3169.
Lin, Q., Wu, L., Ma, Z., Chowdhury, F. A., Mazumder, H. H., & Du, W. (2020). Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function. JCI Insight, 5(10). https://doi.org/10.1172/jci.insight.133365. PMID: 32434992.
Wu, L., Lin, Q., Ma, Z., Chowdhury, F. A., Mazumder, M. H. H., & Du, W. (2020). Mesenchymal PGD2 activates an ILC2-Treg axis to promote proliferation of normal and malignant HSPCs. Leukemia. https://doi.org/10.1038/s41375-020-0843-8. PMID: 32366935
Lin, Q.; Wu, L.; Ma, Z.; Chowdhury, F.A.; Mazumder, H.H.; Du, W.Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function. JCI Insight. May 2020;5(10). doi: 10.1172/JCI.INSIGHT.133365.
Ma, Z., Xu, J., Wu, L., Wang, J., Lin, Q., Chowdhury, F. A., Du, W. (2020). Hes1 deficiency causes hematopoietic stem cell exhaustion. Stem Cells. https://doi.org/10.1002/stem.3169. PMID: 32129527

Jaclyn Connelly

Journal Articles

Zhang, X.; Connelly, J.; Levitan, E.S.; Sun, D.; Wang, J.Q.Calcium/Calmodulin–Dependent Protein Kinase II in Cerebrovascular Diseases. Translational Stroke Research. August 2021;12(4):513-529. doi: 10.1007/s12975-021-00901-9. 
Zhang X, Connelly J, Chao Y, Wang QJ. Multifaceted Functions of Protein Kinase D in Pathological Processes and Human Diseases.   Biomolecules. 2021 Mar 23;11(3):483. doi: 10.3390/biom11030483. PMID: 33807058  PMCID: PMC8005150
 
Zhang X, Connelly J, Levitan ES, Sun D, Wang JQ. Calcium/Calmodulin-Dependent Protein Kinase II in Cerebrovascular Diseases.  Transl Stroke Res. 2021 Aug;12(4):513-529. doi: 10.1007/s12975-021-00901-9. Epub 2021 Mar 13. PMID: 33713030
 
Zhang, X.; Connelly, J.; Chao, Y.; Wang, Q.J.Multifaceted functions of protein kinase d in pathological processes and human diseases. Biomolecules. March 2021;11(3). doi: 10.3390/biom11030483.

Kaylee Ermine

Journal Articles

Tong J, Tan X, Song X, Gao M, Risnik D, Hao S, Ermine K, Wang P, Li H, Huang Y, Yu J, Zhang L. CDK4/6 Inhibition Suppresses p73 Phosphorylation and Activates DR5 to Potentiate Chemotherapy and Immune Checkpoint Blockade. Cancer Res. 2022 Apr 01;82(7):1340-1352. doi: 10.1158/0008-5472.CAN-21-3062.
Tong J, Tan X, Risnik D, Gao M, Song X, Ermine K, Shen L, Wang S, Yu J, Zhang L. BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade. Oncogene. 2021 Dec;40(48):6566-6578. doi: 10.1038/s41388-021-02041-8. Epub 2021 Oct 06.
Kaylee Ermine and Jian Yu and Lin Zhang. Role of Receptor Interacting Protein ({RIP}) kinases in cancer. Genes {\&} Diseases. 2021 nov.
Tong J, Tan X, Risnik D, Gao M, Song X, Ermine K, Shen L, Wang S, Yu J, Zhang L.  BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade. Oncogene. 2021 Oct 6. doi: 10.1038/s41388-021-02041-8. Online ahead of print. PMID: 34615996

Christian Goossen

Journal Articles

Li Y, Kracun D, Dustin CM, El Massry M, Yuan S, Goossen CJ, DeVallance ER, Sahoo S, St Hilaire C, Gurkar AU, Finkel T, Straub AC, Cifuentes-Pagano E, Pagano PJ. Forestalling age-impaired angiogenesis and blood flow by targeting NOX: Interplay of NOX1, IL-6, and SASP in propagating cell senescence. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42). pii: e2015666118.

Victoria Heinrich

Journal Articles

Manni ML, Heinrich VA, Buchan GJ, O’Brien JP, Uvalle C, Cechova V, Koudelka A, Ukani D, Rawas-Qalaji M, Oury TD, Hart R, Ellgass M, Mullet SJ, Fajt ML, Wenzel SE, Holguin F, Freeman BA, Wendell SG. Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma. Eur Respir J. Submitted, under review.
Heinrich VA, Manni ML, Morris A, Wendell SG. Microbial-derived, systemic mediators and lung pathophysiology in obesity-associated asthma. Review in preparation.
Manni ML, Heinrich VA, Buchan GJ, O’Brien JP, Uvalle C, Cechova V, Koudelka A, Ukani D, Rawas-Qalaji M, Oury TD, Hart R, Ellgass M, Mullet SJ, Fajt ML, Wenzel SE, Holguin F, Freeman BA, Wendell SG. Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma. Scientific Reports. 2021; 11(1): 17788.

Angela Hinchie

Journal Articles

Sullivan DI, Jiang M, Hinchie AM, Roth MG, Bahudhanapati H, Nouraie M, et al. Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line. Front Med (Lausanne). 2021;8:600626.
 
Sullivan, D.I.; Jiang, M.; Hinchie, A.M.; Roth, M.G.; Bahudhanapati, H.; Nouraie, M.; Liu, J.; McDyer, J.F.; Mallampalli, R.K.; Zhang, Y.; Kass, D.J.; Finkel, T.; Alder, J.K.Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line. Frontiers in Medicine. 9 February 2021;8. doi: 10.3389/fmed.2021.600626.
Ren, X.; Hinchie, A.; Swomley, A.; Powell, D.K.; Butterfield, D.A.Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease. Free Radical Biology and Medicine. 1 November 2019;143:146-152. doi: 10.1016/j.freeradbiomed.2019.08.008.
Ren X, Hinchie A, Swomley A, Powell DK, Butterfield DA. Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease. Free Radic Biol Med. 2019 01;143:146–52.
 

Lisa Hong

Journal Articles

Lin CC, Mabe NW, Lin YT, Yang WH, Tang X, Hong L, Sun T, Force J, Marks JR, Yao TP, Alvarez JV, Chi JT.  RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. Cell Death Differ. 2020 Jul;27(7):2234-2247. doi: 10.1038/s41418-020-0499-y. Epub 2020 Jan 27. PMID: 31988496
Lin CC, Mabe NW, Lin YT, Yang WH, Tang X, Hong L, Sun T, Force J, Marks JR, Yao TP, Alvarez JV, Chi JT. RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. Cell Death Differ. 2020 Jul;27(7):2234-2247. doi: 10.1038/s41418-020-0499-y. Epub 2020 Jan 27.

Aaron Johnson

Journal Articles

G. L. Seim, E. C. Britt, S. V. John, F. J. Yeo, A. R. Johnson, R. S. Eisenstein, D. J. Pagliarini, J. Fan. 2019. Two-stage metabolic remodeling in macrophages in response to LPS and interferon-γ stimulation. Nature Metabolism 2019, 1 (7) 731-742. Pubmed PMID: 322590
Seim GL, Britt EC, John SV, Yeo FJ, Johnson AR, Eisenstein RS, Pagliarini DJ, Fan J. Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-? stimulation. Nat Metab. 2019 Jul;1(7):731-742. doi: 10.1038/s42255-019-0083-2. Epub 2019 Jul 12.
Card, J.P.; Johnson, A.L.; Llewellyn-Smith, I.J.; Zheng, H.; Anand, R.; Brierley, D.I.; Trapp, S.; Rinaman, L.GLP-1 neurons form a local synaptic circuit within the rodent nucleus of the solitary tract. Journal of Comparative Neurology. 1 October 2018;526(14):2149-2164. doi: 10.1002/cne.24482.

Matthew Keeney

Journal Articles

Keeney MT, Hoffman EK, Farmer K, Bodle CR, Fazzari M, Zharikov A, Castro SL, Hu X, Mortimer A, Kofler JK, Cifuentes-Pagano E, Pagano PJ, Burton EA, Hastings TG, Greenamyre JT, Di Maio R. NADPH oxidase 2 activity in Parkinson's disease. Neurobiol Dis. 2022 Aug;170:105754. doi: 10.1016/j.nbd.2022.105754. Epub 2022 May 13. PMID: 35577065; PMCID: PMC9284948.
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR, Carr SA, Lindquist S, De Jager PL, Bartel DP, Myers CL, Greenamyre JT, Feany MB, Sunyaev SR, Chung CY, Khurana V. The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell. 2022 Jun 09;185(12):2035-2056.e33. pii: S0092-8674(22)00592-X.
Keeney MT, Hoffman EK, Farmer K, Bodle CR, Fazzari M, Zharikov A, Castro SL, Hu X, Mortimer A, Kofler JK, Cifuentes-Pagano E, Pagano PJ, Burton EA, Hastings TG, Greenamyre JT, Di Maio R. NADPH oxidase 2 activity in Parkinson's disease. Neurobiol Dis. 2022 Aug;170:105754. pii: S0969-9961(22)00146-2. Epub 2022 May 13.
Rocha EM, Keeney MT, Di Maio R, De Miranda BR, Greenamyre JT. LRRK2 and idiopathic Parkinson's disease. Trends Neurosci. 2022 Mar;45(3):224-236. pii: S0166-2236(21)00250-2. Epub 2022 Jan 04.
Keeney, M. T., Hoffman, E. K., Greenamyre, J. T. and Di Maio, R. (2021). Measurement of LRRK2 Kinase Activity by Proximity Ligation Assay. Bio-protocol 11(17): e4140. DOI: 10.21769/BioProtoc.4140.
Keeney, M.T., Hoffman E.K., Farmer, K., Bodle, C.R., Fazzari, M., Zharikov, A., Castro, S., Kofler, J., Cifuentes-Pagano, E., Pagano, P.J, Burton, E.A, Hastings, T. G., Greenamyre, J. T, & Di Maio, R. (2021). Neuronal NADPH Oxidase 2 in Parkinson’s Disease Pathogenesis. bioRxiv doi: https://doi.org/10.1101/2021.05.13.443999.
Keeney MT, Hoffman EK, Greenamyre TJ, Di Maio R. Measurement of LRRK2 Kinase Activity by Proximity Ligation Assay. Bio Protoc. 2021 Sep 05;11(17):e4140. doi: 10.21769/BioProtoc.4140. Epub 2021 Sep 05.
Rocha EM, De Miranda BR, Castro S, Drolet R, Hatcher NG, Yao L, Smith SM, Keeney MT, Di Maio R, Kofler J, Hastings TG, Greenamyre JT. LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease. Neurobiol Dis. 2020 Feb;134:104626. pii: S0969-9961(19)30301-8. Epub 2019 Oct 13.
Rocha EM, De Miranda BR, Castro S, Drolet R, Hatcher NG, Yao L, Smith SM, Keeney MT, Di Maio R, Kofler J, Hastings TG, Greenamyre JT.    LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.Neurobiol Dis. 2020 Feb;134:104626. doi: 10.1016/j.nbd.2019.104626. Epub 2019 Oct 13. PMID: 31618685 PMCID: PMC7345850
 

Michelle Lynskey

Journal Articles

Barroso-González J, García-Expósito L, Galaviz P, Lynskey ML, Allen JAM, Hoang S, Watkins SC, Pickett HA, O'Sullivan RJ. Anti-recombination function of MutSa restricts telomere extension by ALT-associated homology-directed repair. Cell Rep. 2021 Dec 07;37(10):110088. pii: S2211-1247(21)01579-5.
Hoang, S.M.; Kaminski, N.; Bhargava, R.; Barroso-González, J.; Lynskey, M.L.; García-Expósito, L.; Roncaioli, J.L.; Wondisford, A.R.; Wallace, C.T.; Watkins, S.C.; James, D.I.; Waddell, I.D.; Ogilvie, D.; Smith, K.M.; da Veiga Leprevost, F.; Mellacharevu, D.; Nesvizhskii, A.I.; Li, J.; Ray-Gallet, D.; Sobol, R.W.; Almouzni, G.; O’Sullivan, R.J.Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. Nature Structural and Molecular Biology. December 2020;27(12):1152-1164. doi: 10.1038/s41594-020-0512-7. 
Hoang SM, Kaminski N, Bhargava R, Barroso-González J, Lynskey ML, García-Expósito L, Roncaioli JL, Wondisford AR, Wallace CT, Watkins SC, James DI, Waddell ID, Ogilvie D, Smith KM, da Veiga Leprevost F, Mellacharevu D, Nesvizhskii AI, Li J, Ray-Gallet D, Sobol RW, Almouzni G, O'Sullivan RJ.  Regulation of ALT-associated homology-directed repair by polyADP-ribosylation.  Nat Struct Mol Biol. 2020 Dec;27(12):1152-1164. doi: 10.1038/s41594-020-0512-7. Epub 2020 Oct 12. PMID: 33046907  PMCID: PMC7809635
 
Barroso-González, J.; Sarkar, S.N.; Watkins, S.C.; O'Sullivan, R.J.; García-Expósito, L.; Hoang, S.M.; Lynskey, M.L.; Roncaioli, J.L.; Ghosh, A.; Wallace, C.T.; Modesti, M.; Bernstein, K.A.Erratum: RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres (Molecular Cell (2019) 76(1) (11–26.e7), (S1097276519305003), (10.1016/j.molcel.2019.06.043)). Molecular Cell. 3 October 2019;76(1):217-. doi: 10.1016/j.molcel.2019.08.009. 
Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, de Vitis M, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ.  RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.   Mol Cell. 2019 Oct 3;76(1):11-26.e7. doi: 10.1016/j.molcel.2019.06.043. Epub 2019 Aug 7. PMID: 31400850  PMCID: PMC6778027
 

Bellina Mushala

Journal Articles

Thapa D, Xie B, Mushala BAS, Zhang M, Manning JR, Bugga P, Stoner MW, Jurczak MJ, Scott I. Diet-induced obese mice are resistant to improvements in cardiac function resulting from short-term adropin treatment. Curr Res Physiol. 2022;5:55-62. doi: 10.1016/j.crphys.2022.01.005. Epub 2022 Jan 25.
Mushala, B., & Scott, I. (2021). Adropin: a hepatokine modulator of vascular function and cardiac fuel metabolism. American journal of physiology. Heart and circulatory physiology, 320(1), H238–H244.
Mushala, B.A.S.; Scott, I.Adropin: A hepatokine modulator of vascular function and cardiac fuel metabolism. American Journal of Physiology - Heart and Circulatory Physiology. January 2021;320(1):H238-H244. doi: 10.1152/AJPHEART.00449.2020.
Thapa, D., Manning, J.R., Mushala, B., Stoner, M.W., Zhang, M. & Scott, I. (2020). Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function. Current Research in Physiology. 3. 44-49
Thapa D, Manning JR, Mushala BAS, Stoner MW, Zhang M, Scott I. Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function. Curr Res Physiol. 2020 Dec;3:44-49. doi: 10.1016/j.crphys.2020.11.001. Epub 2020 Dec 08.

Sonja Plasil

Journal Articles

Baratta, A.M.; Rathod, R.S.; Plasil, S.L.; Seth, A.; Homanics, G.E.Exposure to drugs of abuse induce effects that persist across generations. International Review of Neurobiology. January 2021;156:217-277. doi: 10.1016/bs.irn.2020.08.003.
Plasil SL, Seth A, Homanics GE.  CRISPR Turbo Accelerated KnockOut (CRISPy TAKO) for Rapid in vivo Screening of Gene Function.  Front Genome Ed. 2020 Oct;2:598522. doi: 10.3389/fgeed.2020.598522. Epub 2020 Oct 21. PMID: 33604589 PMCID: PMC7889042
 
Plasil SL, Seth A, Homanics GE. CRISPR Turbo Accelerated KnockOut (CRISPy TAKO) for Rapid in vivo Screening of Gene Function. Front Genome Ed. 2020 Oct;2. pii: 598522. Epub 2020 Oct 21.
Baratta AM, Rathod RS, Plasil SL, Seth A, Homanics GE.  Exposure to drugs of abuse induce effects that persist across generations.  Int Rev Neurobiol. 2021;156:217-277. doi: 10.1016/bs.irn.2020.08.003. Epub 2020 Sep 30. PMID: 33461664  PMCID: PMC8167819
 
Rathod RS, Ferguson C, Seth A, Baratta AM, Plasil SL, Homanics GE.  Effects of Paternal Preconception Vapor Alcohol Exposure Paradigms on Behavioral Responses in Offspring.   Brain Sci. 2020 Sep 22;10(9):658. doi: 10.3390/brainsci10090658. PMID: 32971974 PMCID: PMC7564629
 
Rathod RS, Ferguson C, Seth A, Baratta AM, Plasil SL, Homanics GE. Effects of Paternal Preconception Vapor Alcohol Exposure Paradigms on Behavioral Responses in Offspring. Brain Sci. 2020 Sep 22;10(9) . pii: E658. Epub 2020 Sep 22.

Sripriya Raja

Journal Articles

Raja, S., & Van Houten, B. (2021). The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer.
International journal of molecular sciences, 22(4), 1981. https://doi.org/10.3390/ijms22041981
Raja, S.; Van Houten, B.The multiple cellular roles of smug1 in genome maintenance and cancer. International Journal of Molecular Sciences. 2 February 2021;22(4):1-13. doi: 10.3390/ijms22041981.
Kumar, N.; Raja, S.; Van Houten, B.The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage. Nucleic Acids Research. 18 November 2020;48(20):11227-11243. doi: 10.1093/nar/gkaa777.
Kumar N*, Raja S*, Van Houten B. The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage [published online ahead of print, 2020 Oct 3]. Nucleic Acids Res. 2020;gkaa777. doi:10.1093/nar/gkaa777

Hayley Rein

Journal Articles

Prakash R, Sandoval T, Morati F, Zagelbaum JA, Lim PX, White T, Taylor B, Wang R, Desclos ECB, Sullivan MR, Rein HL, Bernstein KA, Krawczyk PM, Gautier J, Modesti M, Vanoli F, Jasin M. Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex. Nat Commun. 2021 Jul 12;12(1):4255. doi: 10.1038/s41467-021-24205-6. Epub 2021 Jul 12.
Rein, H., Bernstein, K., Baldock, R. (2021), RAD51 paralog function in replicative DNA damage and tolerance, Current Opinions in Genetics and Development, Accepted.
Prakash R, Rawal Y, Sullivan MR, Grundy MK, Bret H, Mihalevic MJ, Rein HL, Baird JM, Darrah K, Zhang F, Wang R, Traina TA, Radke MR, Kaufmann SH, Swisher EM, Guérois R, Modesti M, Sung P, Jasin M, Bernstein KA. Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by comprehensive analysis of cancer variants. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2202727119. doi: 10.1073/pnas.2202727119. Epub 2022 Sep 13.
Rein, H.L., Bernstein, K.A., and Baldock, R.A. (2021) RAD51 paralog function in replicative DNA damage and tolerance. Current Opinions in Genetics and Development, 71:86-91
Prakash, R., Sandoval, T., Morati, F., Zagelbaum, J.A., Taylor, B., Wang, R., Desclos, E.C.B., Sullivan, M.R., Rein, H.L., Bernstein, K.A., Krawczyk, P.M., Gautier, J., Modesti, M., Vanoli, F., Jasin, M. (2021) Distinct pathways homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex, Nature Communications, 12(1):4255
Jiang, Z., Lai, Y., Beaver, J., Tsegay, P., Zhao, M., Horton, J., Zamora,M., Rein, H., Mirales, F., Shaver, M., Hutcheson, J., Agoulnik I., Wilson, S. and Liu, Y. 2020. Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a de novo DNA Methyltransferase. Cells. 9(1):225
Jiang, Z.; Lai, Y.; Beaver, J.M.; Tsegay, P.S.; Zhao, M.-L.; Horton, J.K.; Zamora, M.; Rein, H.L.; Miralles, F.; Shaver, M.; Hutcheson, J.D.; Agoulnik, I.; Wilson, S.H.; Liu, Y.Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase ß and a de novo DNA Methyltransferase. Cells. 16 January 2020;9(1). doi: 10.3390/cells9010225.
Yiming Hao and Feng Cheng and Minh Pham and Hayley Rein and Devashru Patel and Yuchen Fang and Yiyi Feng and Jin Yan and Xueyang Song and Haixia Yan and Yiqin Wang. A Noninvasive, Economical, and Instant-Result Method to Diagnose and Monitor Type 2 Diabetes Using Pulse Wave: Case-Control Study (Preprint). 2018 aug.

Sofya Savransky

Journal Articles

Langowski MD, Khan FA, Savransky S, Brown DR, Balasubramaniyam A, Harrison WB, Zou X, Beck Z, Matyas GR, Regules JA, Miller R, Soisson LA, Batchelor AH, Dutta S. Restricted valency (NPNA)n repeats and junctional epitope-based circumsporozoite protein vaccines against Plasmodium falciparum. NPJ Vaccines. 2022 Jan 27;7(1):13. doi: 10.1038/s41541-022-00430-y. Epub 2022 Jan 27.
Sutkeviciute I, Lee JY, White AD, Maria CS, Peña KA, Savransky S, Doruker P, Li H, Lei S, Kaynak B, Tu C, Clark LJ, Sanker S, Gardella TJ, Chang W, Bahar I, Vilardaga JP. Precise druggability of the PTH type 1 receptor. Nat Chem Biol. 2022 Mar;18(3):272-280. doi: 10.1038/s41589-021-00929-w. Epub 2021 Dec 23.

Anne Wondisford

Journal Articles

Prokhorova E, Agnew T, Wondisford AR, Tellier M, Kaminski N, Beijer D, Holder J, Groslambert J, Suskiewicz MJ, Zhu K, Reber JM, Krassnig SC, Palazzo L, Murphy S, Nielsen ML, Mangerich A, Ahel D, Baets J, O'Sullivan RJ, Ahel I. Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. Mol Cell. 2021 Jun 17;81(12):2640-2655.e8. doi: 10.1016/j.molcel.2021.04.028. PMID: 34019811; PMCID: PMC8221567.
Prokhorova E, Agnew T, Wondisford AR, Tellier M, Kaminski N, Beijer D, Holder J, Groslambert J, Suskiewicz MJ, Zhu K, Reber JM, Krassnig SC, Palazzo L, Murphy S, Nielsen ML, Mangerich A, Ahel D, Baets J, O'Sullivan RJ, Ahel I. Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. Mol Cell. 2021 Jun 17;81(12) :2640-2655.e8. pii: S1097-2765(21)00357-9. Epub 2021 May 20.
Hoang SM, Kaminski N, Bhargava R, Barroso-González J, Lynskey ML, García-Expósito L, Roncaioli JL, Wondisford AR, Wallace CT, Watkins SC, James DI, Waddell ID, Ogilvie D, Smith KM, da Veiga Leprevost F, Mellacharevu D, Nesvizhskii AI, Li J, Ray-Gallet D, Sobol RW, Almouzni G, O'Sullivan RJ. Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. Nat Struct Mol Biol. 2020 Dec;27(12) :1152-1164. doi: 10.1038/s41594-020-0512-7. Epub 2020 Oct 12.
Hoang, S.M.; Kaminski, N.; Bhargava, R.; Barroso-González, J.; Lynskey, M.L.; García-Expósito, L.; Roncaioli, J.L.; Wondisford, A.R.; Wallace, C.T.; Watkins, S.C.; James, D.I.; Waddell, I.D.; Ogilvie, D.; Smith, K.M.; da Veiga Leprevost, F.; Mellacharevu, D.; Nesvizhskii, A.I.; Li, J.; Ray-Gallet, D.; Sobol, R.W.; Almouzni, G.; O’Sullivan, R.J.Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. Nature Structural and Molecular Biology. December 2020;27(12):1152-1164. doi: 10.1038/s41594-020-0512-7. 
Hoang SM, Kaminski N, Bhargava R, Barroso-González J, Lynskey ML, García-Expósito L, Roncaioli
JL, Wondisford AR, Wallace CT, Watkins SC, James DI, Waddell ID, Ogilvie D, Smith KM, da Veiga
Leprevost F, Mellacharevu D, Nesvizhskii AI, Li J, Ray-Gallet D, Sobol RW, Almouzni G, O'Sullivan RJ.
Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. Nat Struct Mol Biol.
2020 Oct 12. doi: 10.1038/s41594-020-0512-7. PMID: 33046907 PMCID: PMC7809635