Skip to Main Content
Pitt Home
Find People
School of Medicine
Toggle navigation
Skip Navigation Links
Home
About
Leadership
Mission
Department Statistics
Building Information
Thomas E. Starzl BST
Biomedical Science Tower 3
Conference Rooms
BSTWR E1347 - Wingard/Lazo Conference Room
BSTWR 1395
Shops
Cell Biology/Pharmacology Machine Shop
Directory
Primary Faculty
Secondary Faculty
Graduate Students
Fellows
Administrative Staff
Research Staff
Adjunct Faculty
Department Alumni
Research
Research Areas
Labs
Equipment
Non-PC&B Personnel Core Facilities Access Request
Funding Opportunities
Faculty Development Program
Responsible Conduct of Research
Education
Molecular Pharmacology Graduate Program
Current Students
Current Student Roster
Student Publications
Diversity, Accessibility, and Counseling
Student Awards
MPGP News
Student Poster and Presentation Resources
Prospective Students
Welcome from the Director
Research Opportunities
PhD Track
MD/PhD Track
Financial Aid
Graduate Faculty
Admin Staff
Graduate Courses
Lab Rotations
Events
Grad Student Event Calendar
Graduate Student Event Schedule
Alumni/Career Development
Alumni
Alumni Contacts
Molecular Pharmacology Facebook Group
Molecular Pharmacology Student-Alumni Network (LinkedIn)
SOM Graduate Studies - Career and Professional Development
Executive Committee
Student Testimonials
IBGP
Funding Opportunities
NIH T32 Training Grant
Outcomes
Predoctoral Fellowship
Admissions
Student Handbook & General Timeline
Links
Useful Links
School of Medicine
PubMed
Remote Resources
Biomedical Masters Program
Undergraduate Research
Summer Fellowships
Lab Rotations
Graduate Fellowships
News
Events
Calendar
Seminar Series
Links
Contact
Opportunities
Department
PORtal
Computer Resources Access Request
IT-Equipment-Facilities Support Request
Poster Requests
Reservation Calendars
Badge Access Request
Home
>
Events
>
Calendar
>
"Exploring the role of progranulin on blood pressu...
Pharmacology & Chemical Biology Seminar Series
4/11/2024 - 12:00 PM-1:00 PM
"Exploring the role of progranulin on blood pressure regulation"
Thiago Bruder do Nascimento, PhD
Assistant Professor
Department of Pediatrics
University of Pittsburgh School of Medicine
Progranulin (PGRN) is extensively researched in neurodegenerative disorders due to its crucial role; its deficiency can lead to frontotemporal dementia (FTD) and may contribute to the onset of Alzheimer's and Parkinson's diseases. However, its impact on vascular biology and blood pressure regulation remains poorly understood. This seminar aims to elucidate the beneficial effects of PGRN in regulating endothelial biology, vascular tone, and blood pressure. It will specifically investigate the autocrine mechanisms by which endothelial PGRN modulates vascular tone and blood pressure, while also demonstrating that PGRN elicits distinct effects in large and small arteries.
Thomas E. Starzl Biomedical Science Tower
1395 Conference Room
200 Lothrop St
Pittsburgh, PA 15213
Contact
Melanie Hoffner