The department has trained graduate students in Pharmacology and Chemical Biology for over 50 years. Alumni who have graduated since 2000 are listed below. Alumni listed here come from a variety of School of Medicine graduate programs, but have all trained with Pharmacology and Chemical Biology primary faculty. Molecular Pharmacology alumni trained with the program's graduate faculty, who are appointed in departments across the School of Medicine.
Jaclyn Connelly (MED '23) Advisor Qiming Jane Wang, PhD Dissertation The Role of Protein Kinase D2 in Ischemic Stroke (2023) Sripriya Raja (MED '23) Advisor Ben Van Houten, PhD Dissertation Understanding the role of UV-DDB in the SMUG1 mediated repair of oxidative DNA (2023) Hayley Rein (MED '23) Advisor Kara Bernstein, PhD Dissertation Functional Characterization RAD51C Cancer Associated Variants of Unknown Significance (2023) Aaron Johnson (MED '23) Advisor Sruti Shiva, PhD Dissertation Myoglobin attenuates breast cancer cell proliferation and migration (2023) Joseph Galley (MED '21) Advisor Adam C. Straub, PhD Dissertation Mechanisms of Guanylyl Cyclase Gene Regulation by FoxO Transcription Factors (2021) Anastasia Gorelova (MED '20) Advisor Imad Al Ghouleh, PhD Dissertation The Role of EBP50 in Regulating Endothelial-To-Mesenchymal Transition in Pulmonary Hypertension (2020) Zheqi Li (MED '20) Advisor Steffi Oesterreich, PhD Dissertation Hotspot Mutations on Estrogen Receptor-a Are Multimodal and Contextual Drivers of Breast Cancer Endocrine Resistance and Metastasis (2020) Braulio Bonilla (MED '20) Advisor Kara A. Bernstein, PhD Dissertation The budding yeast Shu complex promotes the error-free bypass of abasic sites and 3-methylcytosines (2020) Gregory Buchan (MED '19) Advisor Bruce A. Freeman, PhD Dissertation Formation and signaling of electrophilic lipids in immunity (2019) Song-My Hoang (MED '19) Advisor Roderick J. O'Sullivan, PhD Dissertation Control of telomeric homology-directed repair by poly(ADP-ribose) metabolism (2019) Nolan Carew (MED '19) Advisor Adam C. Straub, PhD Joshua Lorenz - Guertin (MED '19) Advisor Tija C. Jacob, PhD Dissertation REGULATION OF GABAAR SIGNALING AND NEUROADAPTATIONS IN RESPONSE TO DIAZEPAM. (2019) Alparslan Asan (MED '19) Advisor Carola Neumann, MD Dissertation Nitroalkene Repression of Homologous Recombination as a Treatment for Triple Negative Breast Cancer (2019) Shireen Attaran (MED '18) Advisor Carola Neumann, MD Dissertation INVESTIGATING THE INFLUENCE OF OXIDATIVE STRESS AND THE ROLE OF PRDX1 IN THE REGULATION OF LYSYL OXIDASE MEDIATED ECM AND COLLAGEN REMODELING IN BREAST CANCER METASTASIS Emily Bossart (MED '18) Advisor Steffi Oesterreich, PhD Dissertation Investigation of EMT-like Phenotypes in Established and Novel Model Systems of Invasive Lobular Breast Carcinoma Rochelle Fletcher (MED '18) Advisor Lin Zhang, PhD Dissertation The Role of NSAID-Induced ER Stress and Immunomodulation in the Suppression of Colorectal Tumorigenesis Soma Jobbagy (MED '18) Advisor Francisco J. Schopfer, PhD Dissertation Impact of Nrf2 signaling on thiol homeostasis and renal physiology Alison Nagle (MED '18) Advisor Adrian Lee, PhD Dissertation Credentialing IGF1R pathway activation as a novel therapeutic target in E-cadherin deficient breast cancer Nyla Naim (MED '18) Advisor Daniel Altschuler, PhD Dissertation LUMINESCENCE-ACTIVATED CYCLASE ALLOWS LOCALIZED PHOTO AND CHEMICAL STIMULATION OF cAMP SYNTHESIS (2018) Vera Procaccia (MED '18) Advisor Dr. Alessandro Bisello Dissertation THE SCAFFOLDING PROTEIN EBP50 REGULATES MITOCHONDRIAL DYNAMICS AND REDOX BALANCE IN VASCULAR SMOOTH MUSCLE CELLS Nicholas Smith (MED '18) Advisor Adrian Lee, PhD Nolan Priedigkeit (MED '17) Advisor Adrian Lee, PhD Dissertation Identification of acquired molecular dependencies in advanced breast and ovarian cancers Chen-Shan (Julia) Woodcock (MED '17) Advisor Bruce A. Freeman, PhD Dissertation Therapeutic Potential of Electrophilic Nitro-Oleic Acid for The Treatment of Triple-Negative Breast Cancer Courtney Andersen (MED '16) Advisor Steffi Oesterreich, PhD Dissertation TARGETING ESTROGEN RECEPTOR AS A STRATEGY FOR PERSONALIZED MEDICINE IN OVARIAN CANCER Kyle Knickelbein (MED '16) Advisor Lin Zhang, PhD Dissertation Mechanisms and Novel Therapeutic Approaches for KRAS-Mediated Resistance to Anti-EGFR Therapy in Colorectal Cancer Cells (2016) Andrea Braganza (MED '15) Advisor Robert W. Sobol, PhD Dissertation UBE3B is a mitochondria-associated E3 ubiquitin ligase whose activity is modulated by its interaction with Calmodulin to respond to oxidative stress Noah Peyser (MED '15) Advisor Jennifer Grandis, MD Dissertation PTPRT/D MUTATION OR PROMOTER METHYLATION: IMPLICATIONS FOR STAT3 INHIBITION Atif Towheed (MED '15) Advisor Michael J. Palladino, PhD Dissertation Allotopic RNA expression strategy to rescue an endogenous mitochondrial ATP6[1] mutation in Drosophila Anny Treat (Caceres) (MED '15) Advisor Guillermo G. Romero, PhD Dissertation THE ROLE OF NHERF1/EBP50 IN WNT SIGNALING IN THE EPITHELIUM Wai Kan (Karen) Chiu (MED '14) Advisor Michael J. Palladino, PhD Dissertation Mitochondrial Allotopic Gene Therapy Approaches Using a Drosophila Model with an Endogenous ATP6 Mutation Daniel Ranayhossaini (MED '14) Advisor Patrick J. Pagano, PhD Dissertation Rational Design and Therapeutic Potential of a Novel Nox1 Inhibitor for the Treatment of Pulmonary Hypertension: In Vitro and In Vivo Effects of Nox1 Inhibition Bartholomew Roland (MED '14) Advisor Michael J. Palladino, PhD Dissertation An in vivo structure-function analysis of the pathogenesis of triosephosphate isomerase deficiency Kristen Leslie (Balogh) (MED '13) Advisor Dr. Alessandro Bisello Dissertation Exploring the Role of EBP50 in Vascular Inflammation Ranmal Samarasinghe (MED '13) Advisor Donald B. DeFranco, PhD Cassandra Henry (MED '12) Advisor Jill M. Siegfried, PhD Jeffrey Koenitzer (MED '12) Advisor Bruce A. Freeman, PhD Dissertation Electrophillic Nitro-Fatty Acid Regulation of Mitochondrial Function Shoghag B Panjarian (MED '12) Advisor Thomas E. Smithgall, PhD Dissertation Investigating Allosteric Regulation of ABL and BCR-ABL Kinases: Implications for Small Molecule Inhibitors Kelly Quesnelle (MED '12) Advisor Jennifer Grandis, MD Dissertation Intracellular Signaling Mechanisms of Resistance to TGFR-Targeting Agents David Svilar (MED '12) Advisor Robert W. Sobol, PhD Dissertation DNA Glycosylases as Modulators of Chemotherapeutic Response Man Yan Wong (MED '12) Advisor Edwin S. Levitan, PhD Dissertation Delivery and Exocytosis of Neuropetide Vesicles at the Nerve Terminal Amy M Furda Romesberg (MED '11) Advisor Ben Van Houten, PhD Dissertation The role of mtDNA damage in mitochondrial dysfunction Eva M Goellner (MED '11) Advisor Robert W. Sobol, PhD Dissertation Demonstrating functional crosstalk between DNA base excision repair and cellular bioenergetics: A strategy for the treatment of chemotherapy resistant glioblastoma Melanie J Grubisha (MED '11) Advisor Donald B. DeFranco, PhD Dissertation TGFBeta-Dependent ROS Regulates a Local Endocrine Communication Network Between Stromal and Epithelial Cells in the Prostate Courtney R LaValle (MED '11) Advisor Qiming Jane Wang, PhD Dissertation Targeting Protein Kinase D by Novel Small Molecule Inhibitors and RNA Interference in Prostate Cancer Nicholas W Bateman (MED '10) Advisor Thomas P. Conrads, PhD Dissertation A Proteomic Analysis of Neoplastic Progression in Breast Cancer Austin Dulak (MED '10) Advisor Jill M. Siegfried, PhD Dissertation Analyzing the Impact of EGFR-induced c-Met Phosphorylation in Non-Small Cell Lung Cancer Carolyn A Kitchens (MED '10) Advisor John S. Lazo, PhD Dissertation Exploitation of Small Interfering RNA Methodology to Identify Novel Anticancer Treatments Yan Wang (MED '10) Advisor John S. Lazo, PhD Dissertation Uncovering the Biological Functions of Phosphatase of Regenerating Liver-2 David Wheeler (MED '10) Advisor Peter A. Friedman, PhD Guillermo G. Romero, PhD Dissertation The PDZ adaptor protein, NHERF1, organizes and regulates protein complexes at the cell membrane Alison Groeger (MED '09) Advisor Bruce A. Freeman, PhD Dissertation Discovery and Characterization of Inflammation-induced Electrophilic Fatty Acid Derivatives Michael Hezel (MED '09) Advisor Ferruccio Galbiati, PhD Dissertation LGMD-1C: Role of Caveolin-3 in Neuromuscular Junction Structure and Function Pierre Queiroz de Oliveira (MED '09) Advisor John S. Lazo, PhD Dissertation Elucidating the role of Cdc25A in hypoxia-mediated cell cycle arrest Alexander Bank (MED '08) Advisor Lin Zhang, PhD Dissertation The Role of SMAC in NSAID-induced Apoptosis Janine N Bartholomew (MED '08) Advisor Ferruccio Galbiati, PhD Dissertation Caveolin-1 mediated p53 activation in stress induced premature senescence and its antagonistic pleiotropic implications in cancer John Caltagarone (MED '08) Advisor Donald B. DeFranco, PhD Dissertation Differential Localization of Hic-5 and Paxillin in the Brain of Alzheimer's Disease Subjects Peter R McDonald (MED '08) Advisor John S. Lazo, PhD Dissertation Identification of Novel Potential Cancer Therapies by Synthetic Lethal Screening Robert Tomko (MED '08) Advisor John S. Lazo, PhD Dissertation Cellular and Biochemical Regulation of Cdc25A Phosphatase by Nitrosative Stress Pallavi Bansal (MED '07) Advisor John S. Lazo, PhD Dissertation Induction of CD25B Following DNA Damage: Implications for Cell Cycle Resumption and Tumorigenesis David F Werner (MED '07) Advisor Gregg E. Homanics, PhD Dissertation Elucidating the Role of a i-Contacting Gaba (A) Receptors in Ethanol Action John H Dubinion (MED '06) Advisor Edwin K. Jackson, PhD Dissertation Modulation of Angiotensin II-Induced Renal Vascular Presponses by PP-Fold Peptides Maria S Santos (MED '06) Advisor Ian J. Reynolds, PhD Dissertation Mitochondrial DNA in neurons and its modulation by neurotoxins Prajakta Sonalker (MED '06) Advisor Edwin K. Jackson, PhD Dissertation The Renal Bumetaride-Sensitive Na-K-2Cl Cotransporter BSC-1/NKCO2 in Essential Hypertension and Its Regulation by Norepinephrine Diane T.W. Chang (MED '05) Advisor Ian J. Reynolds, PhD Dissertation Mitochondrial Trafficking in Healthy and Injured Neurons (2005) Catherine Kraft (MED '05) Advisor Guillermo G. Romero, PhD Dissertation Lipid Binding and the Scaffolding function of the Kinase Suppressor of Ras Latha Malaiyandi (MED '05) Advisor Ian J. Reynolds, PhD Dissertation Interactions between Zinc and Mitochondria in Neuronal Injury Alex Ducruet (MED '04) Advisor John S. Lazo, PhD Dissertation Regulation of CDC25A in Human Tumor Cells by Cyclin-Dependent Kinase 2 Susana Montoya (MED '04) Advisor John S. Lazo, PhD Dissertation Evaluation of the Physiological Functions of Bleomycin Hydrolase in the Murine CNS Brad Andresen (MED '02) Advisor Guillermo G. Romero, PhD Dissertation Angiotensin II Signaling to Phospholipase D in a Model of Genetic Hypertension Ron Bernardi (MED '02) Advisor Candace S. Johnson, PhD Dissertation Vitamin D in Cancer Therapy: Mechanistic Studies and Novel Combinations Kirk Dineley (MED '02) Advisor Ian J. Reynolds, PhD Dissertation An Investigation of the Neurotoxic Properties of Zinc Lefteris Zacharia (MED '02) Advisor Edwin K. Jackson, PhD Dissertation Protective Role of the 2-Hydroxyesteradiol Methylation Pathway in the Cardiovascular and Renal Systems: Interaction with Catecholamines Yuen-Keng Ng (MED '01) Advisor Edwin S. Levitan, PhD Dissertation Enhancement of Neuropeptide Release by Increasing the Mobility of Secretory Granuler Yadi Tan (MED '01) Advisor Leaf Huang, PhD Dissertation Overcoming the Inflammatory Toxicity in Cationic Lipid Vector Mediated System Gene Delivery Ting-Ting Zhang (MED '01) Advisor Edwin S. Levitan, PhD Dissertation Regulation of KU4.3 and KV1.5KV Potassium Channel Expression in Cardiac Mycytes and GH3 Pituitary Cells Megan Rizzo (MED '00) Advisor Guillermo G. Romero, PhD Dissertation The Role of Phospholipase D in the Regulation of the Mitogen-Activated Protein Kinase Cascade Joelle Scanlon (MED '00) Advisor Ian J. Reynolds, PhD Dissertation The Role of Mitochondria in Glutamate-Induced Neuronal Injury Mark Whitmore (MED '00) Advisor Leaf Huang, PhD Dissertation Antitumor Activity of the LPD Lipopolyplex Prepared with Immunostimulatory CpG DNA Heidi Schmidt (MED ') Advisor Adam C. Straub, PhD Dissertation "Unraveling Novel Roles of Xanthine Oxidase in Sickle Cell Disease" (2022) (22)