Pharmacology & Chemical Biology Seminar Series
9/27/2018 - 12:00 PM-1:00 PM
“An unbiased chemical biology approach to understanding the mechanisms mediating tauopathy”



Tauopathies are a group of neurodegenerative diseases characterized pathologically by abnormal aggregates of the microtubule-associated protein tau in neurons and glia.  The mechanisms relating tau accumulation to neurological dysfunction and cell death are not understood and there are no effective treatments for these diseases.  Our work exploits novel zebrafish tauopathy models to dissect the underlying molecular pathogenesis, using unbiased screens and medium-throughput reverse genetics.  The seminar will focus on a chemical biology approach to understanding tauopathy in vivo using these models.
 

Edward Burton, M.D., DPhil, FRCP (UK)

Associate Professor, Neurology
University of Pittsburgh School of Medicine

Thomas E. Starzl Biomedical Science Tower
1395 Conference Room
203 Lothrop Street
Pittsburgh, PA 15213
Contact
Melanie McClain
4123837757
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Events

Graduate Student Summer Seminar
Presented by Braulio Bonilla and Nolan Carew
Thomas E. Starzl Biomedical Science Tower
1395 Conference Room

Recent Publications

Program Achievements

Molecular Pharmacology Graduate Program Ranked #2 in National Research Council Rankings

Outcomes: 

Time to dissertation Defense
, last five graduating classes:  4.6 years, Completion Rate: 86.49%

First Author Publications (All students, past 5 year mean):  2.03;   Total Publications: 5.10

F-series Grants (F30/F31) (All Students, past 5 year mean):  12/34 (35%) 


Ranked #9 in National of Institute of Health funding of departments of Pharmacology

Ranked in the top 15 in funding for twenty-four consecutive years