These are some of the research opportunities available to students of the MPGP: Cancer Pharmacology Oncogenes and tumor suppressors Cell cycle regulation Mechanisms of DNA repair Chemoprevention of cancer Biomarkers for tumor progression Cardiovascular and Renal Pharmacology Regulation of blood pressure Calcium and phosphate homeostasis Vascular effects of reactive oxygen species Drug Discovery Design and development of high throughput drug screening methodologies Novel chemotherapeutic agents Combinatorial chemistry Neuropharmacology Mechanisms of neurotoxicity Regulation of ion channels Regulation of the autonomic nervous system Neuronal vesicle transport and mechanisms of synaptic transmission Pharmacology of addiction Pharmacology of Cell and Organ Systems Signal Transduction Structure and function of G protein coupled receptors Signaling and cancer Regulation of cellular processes by free radicals and nitric oxide derivatives Nuclear receptors Protein kinases and phosphatases