Alumni Courtney LaValle2011

Targeting Protein Kinase D by Novel Small Molecule Inhibitors and RNA Interference in Prostate Cancer (2011)

Advisor: Qiming Jane Wang, PhD

Science Core Facility Technician, Department of Biology, University of Puget Sound, Tacoma

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Carolyn Kitchens2011

Exploitation of Small Interfering RNA Methodology to Identify Novel Anticancer Treatments (2011)

Advisor: John Lazo, PhD

Post Doctoral Associate, Department of Pharmacology and Chemical Biology, University of Pittsburgh

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Serah Choi2011

Preclinical Studies on ATM Kinase Inhibitors As Anti-Cancer Agents (2011)

Advisor: Chris Bakkenist, PhD

Medical Student, School of Medicine, University of Pittsburgh, Pittsburgh

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Amy Furda2011

The role of mtDNA damage in mitochondrial dysfunction (2011)

Advisor: Ben Van Houten, PhD

Instructor, Health Care Career Training, Sanford-Brown Institute

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Eva Goellner2011

Demonstrating functional crosstalk between DNA base excision repair and cellular bioenergetics: A strategy for the treatment of chemotherapy resistant glioblastoma (2011)

Advisor: Robert Sobol, PhD

Postdoctoral Associate, Ludwig Institute for Cancer Research, University of California-San Diego

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Melanie Grubisha2011

TGFBeta-Dependent ROS Regulates a Local Endrocrine Communication Network Between Stromal and Epithelial Cells in the Prostate (2011)

Advisor: Donald DeFranco, PhD

Medical Student, School of Medicine, University of Pittsburgh

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David Wheeler2010

The PDZ adaptor protein, NHERF1, organizes and regulates protein complexes at the cell membrane (2010)

Advisor: Guillermo Romero, PhD

Medical Student, School of Medicine, University of Pittsburgh

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Nicholas Bateman2010

A Proteomic Analysis of Neoplastic Progression in Breast Cancer (2010)

Advisor: Thomas Conrads, PhD

Postdoctoral Associate, Department of Cell Biology and Physiology, University of Pittsburgh

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Austin Dulak2010

Analyzing the Impact of EGFR-induced c-Met Phosphorylation in Non-Small Cell Lung Cancer (2010)

Advisor: Jill Siegfried, PhD

Postdoctoral Associate, Harvard University, Dana-Farber Cancer Institute, Medical Oncology

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Yan Wang2010

Uncovering the Biological Functions of Phosphatase of Regenerating Liver-2 (2010)

Advisor: John Lazo, PhD

Postdoctoral Associate, Department of Pediatrics, Children's Hospital of Pittsburgh

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Sangeetha Iyer2010

Role of the Alpha 4-containing GABA A Receptors in anesthetic and Ethanol Antagonist Effects: Insights from a Global Knockout Mouse Model (2010)

Advisor: Gregg Homanics, PhD

Postdoctoral Fellow, Section of Neurobiology, College of Natural Sciences, University of Texas, Austin

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Jonathan Beckel2009

Expression and Function of Urothelial Nicotinic Acetylcholine Receptors (2009)

Advisor: Lori Birder, PhD

Postdoctoral Researcher, Department of Anatomy and Cell Biology, School of Medicine, University of Pennsylvania

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Pierre Queiroz de Oliveira2009

Elucidating the role of Cdc25A in hypoxia-mediated cell cycle arrest (2009)

Advisor: John Lazo, PhD

Technical Specialist, Pepper Hamilton LLP, Attorneys at Law

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Neil Bhola2009

Investigation of the mechanisms and therapeutic implications of crosstalk between G-protein-coupled receptors and the Epidermal Growth Factor Receptor in HNSCC (2009)

Advisor: Jennifer Grandis, MD

Post Doctoral Researcher, Cancer Biology, Vanderbilt-Ingram Cancer Center, Vanderbilt University

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Teodora Pene-Dumitrescu2009

Investigating the SRC kinase HCK functions in Chronic Myelogenous Leukemia using chemical genetics methods (2009)

Advisor: Thomas Smithgall, PhD

Quintiles Clinical Pharmacokinetics/Pharmacodynamics Fellow, University of North Carolina at Chapel Hill, School of Pharmacy,

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Joshua Snyder2009

Epithelial Reparative Capacity Regulates Extracellular Matrix Dynamics and Innate Immunity (2009)

Advisor: Barry Stripp, PhD

Postdoctoral Fellow, Duke University Medical School, Cell Biology

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Alison Groeger2009

Discovery and Characterization of Inflammation-induced Electrophilic Fatty Acid Derivatives (2009)

Advisor: Bruce Freeman, PhD

San Francisco, CA

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Miranda Sarachine2009

Roles of the Estrogen Receptors and the Nuclear Matrix in Breast Cancer Development and Tamoxifen Resistance (2009)

Advisor: Billy Day, PhD

Postdoctoral Research Staff, Lawrence Livermore National Laboratory, Center for Accelerator Mass Spectrometry

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Michael Hezel2009

LGMD-1C: Role of Caveolin-3 in Neuromuscular Junction Structure and Function (2009)

Advisor: Ferruccio Galbiati, PhD

Post Doc Researcher, Pharmacological Nitric Oxid Research, Karolinska Institutet, Stockholm, Sweden

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Robert Tomko2008

Cellular and Biochemical Regulation of Cdc25A Phosphatase by Nitrosative Stress (2008)

Advisor: John Lazo, PhD

Postdoctoral Associate, Yale University, Molecular Biophysics and Biochemistry

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Alexander Bank2008

The Role of SMAC in NSAID-induced Apoptosis (2008)

Advisor: Lin Zhang, PhD

Scientist, Qiagen

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Janine Bartholomew2008

Caveolin-1 mediated p53 activation in stress induced premature senescence and its antagonistic pleiotropic implications in cancer (2008)

Advisor: Ferruccio Galbiati, PhD

Assistant Professor, Biology, Carlow University

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John Caltagarone 2008

Differential Localization of Hic-5 and Paxillin in the Brain of Alzheimer's Disease Subjects (2008)

Advisor: Donald DeFranco, PhD

Postdoctoral Associate, Cell Biology and Physiology, University of Pittsburgh

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Dev Chandra2008

Extrasynaptic GABA Type A Receptors in the Mechanism of Action of Ethanol (2008)

Advisor: Gregg Homanics, PhD

Post-Doctoral Fellow, Neurology, University of California-San Francisco

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Peter McDonald2008

Identification of Novel Potential Cancer Therapies by Synthetic Lethal Screening (2008)

Advisor: John Lazo, PhD

Research Associate, Structural Biology Center, The University of Kansas

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Gregory Gan2007

Human REV3L Expression and Protein Interaction Studies (2007)

Advisor: Richard D. Wood, Ph.D.

Resident, Radiation Oncology, University of Colorado, Denver

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Jenny Linnoila2007

T1di Mediates Agrin and Muscle Specific Kinase Signaling at the Neuromuscular Junction (2007)

Advisor: Zuo-Zhong Wang, PhD

Neurology Resident, Massachusetts General Hospital, Boston

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Pallavi Bansal2007

Induction of CD25B Following DNA Damage: Implications for Cell Cycle Resumption and Tumorgenesis (2007)

Advisor: John Lazo, PhD

Marketing Program - Novartis

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Hirdesh Uppal2007

Regulatory Networks of PXR, Car and LXR in Cholesterol and Bile Acid Metabolism (2007)

Advisor: Wen Xie, MD, PhD

Scientist, Genentech, Inc.

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David Werner2007

Elucidating the Role of a i-Contacting Gaba (A) Receptors in Ethanol Action (2007)

Advisor: Gregg Homanics, PhD

Assistant Professor of Psychology, Center for Development & Behavioral Neuroscience, SUNY-Binghamton

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Prajakta Sonalker2006

The Renal Bumetaride-Sensitive Na-K-2Cl Cotransporter BSC-1/NKCO2 in Essential Hypertension and Its Regulation by Norepinephrine (2006)

Advisor: Edwin Jackson, PhD

New York University, Intellectual Property Manager

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John Dubinion2006

Modulation of Angiotensin II-Induced Renal Vascular Presponses by PP-Fold Peptides (2006)

Advisor: Edwin Jackson, PhD

Instructor, Department of Physiology and Biophysics, University of Mississippi

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Maria Santos2006

Mitochondrial DNA in neurons and its modulation by neurotoxins (2006)

Advisor: Ian Reynolds, PhD

Medical Writer, Spain

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Elena Sirbu2006

Screening Assay for Selective Estrogen Receptor Modulators (2006)

Advisor: Mark Nichols, PhD

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Qing Zhang2005

Epidermal Growth Factor Receptor (EGFR) Activation by Gastrin Releasing Peptide (GRP) in Head and Neck Cancer: Mechanisms and Clinical Implications (2005)

Advisor: Jennifer Grandis, MD

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Latha Malaiyandi 2005

Interactions between Zinc and Mitochondria in Neuronal Injury (2005)

Advisor: Ian J. Reynolds, Phd

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Diane T.W. Chang2005

Mitochondrial Trafficking in Healthy and Injured Neurons (2005)

Advisor: Ian J. Reynolds, PhD

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Catherine Kraft 2005

Lipid Binding and the Scaffolding function of the Kinase Suppressor of Ras (2005)

Advisor: Guillermo Romero, PhD

Product Specialist - LSM Systems

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Lori Emert-Sedlak 2005

Meditation of Chemotherapy-Induced Apoptosis by the Lysosomal Protease Cathespin D (2005)

Advisor: Daniel Johnson, PhD

Research Associate, University of Pittsburgh, MMG

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Julie Myers-Irvin 2005

Characterization of Nuclear Matrix Alterations Involved in Bladder Cancer Progression (2005)

Advisor: Robert Getzenberg, PhD

Scientist Administrator, Department of Radiology, University of Pittsburgh

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Susana Montoya 2004

Evaluation of the Physiological Functions of Bleomycin Hydrolase in the Murine CNS (2004)

Advisor: John Lazo, PhD

Research Associate, Department of Neurology, University of Pittsburgh

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Alex Ducruet 2004

Regulation of CDC25A in Human Tumor Cells by Cyclin-Dependent Kinase 2 (2004)

Advisor: John Lazo, PhD

Technology Licensing Manager, Office of Technology Management, University of Pittsburgh

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Haibing Jiang2003

Mechanisms of Polyglutamine Expanded Huntingtin Induced Toxicity (2003)

Advisor: Donald DeFranco, PhD

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Lefteris Zacharia 2002

Protective Role of the 2-Hydroxyesteradiol Methylation Pathway in the Cardiovascular and Renal Systems: Interaction with Catecholamines (2002)

Advisor: Edwin Jackson, PhD

Post-Doc, Clinical Pharmacology, University of Pittsburgh

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Brad Andresen2002

Angiotensin II Signaling to Phospholipase D in a Model of Genetic Hypertension (2002)

Advisor: Edwin Jackson & Guillermo Romero

Assistant Professor, Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences

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Kirk Dineley 2002

An Investigation of the Neurotoxic Properties of Zinc (2002)

Advisor: Ian J. Reynolds, PhD

Associate Professor of Pharmacology, Biology, Roosevelt University

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Ron Bernardi 2002

Vitamin D in Cancer Therapy: Mechanistic Studies and Novel Combinations (2002)

Advisor: Candace S. Johnson, PhD

Assistant Professor, Baylor College of Medicine/Texas Children’s Hospital

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Yadi Tan 2001

Overcoming the Inflammatory Toxicity in Cationic Lipid Vector Mediated System Gene Delivery (2001)

Advisor: Leaf Huang, PhD

Associate Professor, Central China Agriculture University, Wuhan, China

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Yuen-Keng Ng 2001

Enhancement of Neuropeptide Release by Increasing the Mobility of Secretory Granuler (2001)

Advisor: Edwin Levitan, PhD

Research Instructor, Department of Pharmacology and Chemical Biology

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Ting-Ting Zhang 2001

Regulation of KU4.3 and KV1.5KV Potassium Channel Expression in Cardiac Mycytes and GH3 Pituitary Cells (2001)

Advisor: Edwin Levitan, PhD

Post-Doc, Harvard University, Mclean Hospital

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Mark Rizzo 2000

The Role of Phospholipase D in the Regulation of the Mitogen-Activated Protein Kinase Cascade (2000)

Advisor:

Assistant Professor, Department of Physiology, University of Maryland

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Mark Whitmore2000

Antitumor Activity of the LPD Lipopolyplex Prepared with Immunostimulatory CpG DNA (2000)

Advisor: Leaf Huang, PhD

Research Fellow, Cancer Biology, Lerner Research Institution

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Joelle Scanlon 2000

The Role of Mitochondria in Glutamate-Induced Neuronal Injury (2000)

Advisor: Ian J. Reynolds, PhD

Research Associate, Physical Medicine & Rehabilitation, University of Pittsburgh

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Chialin Cheng1999

Relationship Between the Concentration of Intracellular Divalent Cations and Excitotoxicity (1999)

Advisor: Ian J. Reynolds, PhD

Postdoctoral Fellow, Vollum Institute, Oregon Health Sciences University

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Marni Brisson 1999

Development of an Improved Cytoplasmic Expression System for Gene Therapy (1999)

Advisor: James Perel, MD

Research Assistant Professor, Depatrment of Pharmacology and Chemical Biology, University of Pittsburgh

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Edwina Lerner1997

Targeting Ras Prenylation in Anti-Cancer Therapy (1997)

Advisor: Said M. Sebti, PhD

Research Instructor, Department of Pharmacology and Chemical Biology, University of Pittsburgh

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Dung Luong Thai1997

Asymmetric Synthesis, Pharmacology, and Pharmacokinetics of the Three Enantiomers of methyphenidate and their Para-Substituted Analogues (1997)

Advisor: James Perel, MD

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James White, III1996

A Complex Interrelationship between Cyctoplasmic Calcium Homeostasis and Mitochondrial Physiology in Cultured Forebrain Neurons (1996)

Advisor: Ian J. Reynolds, PhD

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Lina Khalil Charles Rudolf Sovan1996

Aspects of B Cell Differentiation and Apoptosis (1996)

Advisor: Christine Milcarek, PhD,Justus Cohen, PhD, Ronald Goldfarb, PhD

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Karl Rene Hoyt1996

Dopamine and Glutamate Interactions in Cultured Neurons (1996)

Advisor: Ian J. Reynolds, PhD

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James Michael Rusnak1995

Protein Kinase Ce Modulation of Higher Order Chromatin Cleavage in Apoptotic Androgen-Independent Human Prostatic Carcinoma Cells (1995)

Advisor: John Lazo, PhD

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Sunita Rajdev1995

Glutamate-Induced Changes in Intracellular Calcium and Magnesium in Rat Forebrain Neurons in Bitro: Relationship to Excitotoxicity (1995)

Advisor: Ian J. Reynolds, PhD

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Jianhua Zhou1994

Clinical Variability in Inerited Sodium Chennelopathies: Studies of heterogeneity at the Gene and Gene Expression Levels (1994)

Advisor: Eric P. Hoffman, PhD

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Susan C. Croll1992

Role of Mesage Turnover in Influencing the Abundance of B Cell mRNAs During Ontogeny (1992)

Advisor: Christine Milcarek, PhD

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Ann Marie Mackway Wells1984

The Effects of Methylphenidate and amphetamine on Synaptosomal Uptake, Prolactin, and Linear Growth in Rat Pups-A Model of Pharmacological Effects (1984)

Advisor: James Perel, MD

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Charles R. Mantione1983

Ethylcholine Aziridinum: A New Cholinergic Specific Presynaptic Toxin (1983)

Advisor: Israel Hanin, PhD

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Gary Leopold Nieder1981

Lactate and Pyruvate Levels in the Mouse Oviduct (1981)

Advisor: Robert H. Connamacher, PhD

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Jacob Krier1977

Autonomic Control of the Colon of the Cat (1977)

Advisor: William de Groat, PhD

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John Mark Braughler1977

Studies on the Sodium-Potassium Dependednt Adenosine Triphosphate from Human Renal Tissue (1977)

Advisor: Clinton N. Corder, PhD

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Jackson Thomas Wright Jr.1977

Isolation, Partial Characterization, and Distribution of Rat Kidney NAD+-Dependent/5-Hydroxyprostaglandin Dehydrogenase (1977)

Advisor: Clinton N. Corder, PhD

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William H. Thies1972

An Investigation of the Cholinergic System of the Isolated Electroplaque from Electrophorus Electrices (1972)

Advisor: Henry B. Higman, PhD

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Dale Bernard Evans1967

Stimulatory Effects of Acetylcholine on Rate of the Intact Atropinized Cat Heart (1967)

Advisor: Paul L. McLain, PhD

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Richard J. Schneider

The Effects of Leisons of the Posterior Funiculi of Macaca Mulatta ()

Advisor:

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